Biomedical subjects

Víctor Azurmendi Sastre

Publications and source records attributed to Víctor Azurmendi Sastre.

10 recordsLinked to original sources

PubMed2005

[Non germinal cell testicular tumors].

OBJECTIVES: We report a review of all patients with testicular tumors undergoing surgery in our Hospital over a 13 year period. There were 151 cases, 50 of them were reported as non germ cell tumors (33%). METHODS/RESULTS: 42% of them were haematopoietic tumors, lymphomas and leukemias. 30% of them were non neoplastic tumors, including vascular tumors and granulomatous orchitis. 12% were identified as Leydig or Sertoli cell tumors. 10% were metastases. CONCLUSIONS: Non germ cell tumors were more frequent in adults (78%) than in children (22%). Among children, 82% of the neoplasias were leukemic infiltration of the testicle.

Adolescent↗

PubMed2004

[Adrenal spindle cell angiosarcoma. Report one case].

OBJECTIVES: To report a new case of spindle cell angiosarcoma of the adrenal gland. METHODS: We reviewed 22 cases previously published of this rare entity, analyzing at the same time both clinical and pathologic findings of this infrequent sarcoma of urological localization. The epithelioid variety is the most common, which makes our spindle cell type case rarer, if possible. RESULTS: 59-year-old male without significant previous medical history presenting at the emergency department with sudden onset of pain in the left hemithorax after several months of discomfort in the area. Diagnostic imaging tests showed a heterogeneous mass dependent of the left kidney. After performing radical nephrectomy and adrenalectomy, pathologic and immunohistochemical studies offered the diagnosis. CONCLUSIONS: Despite the rarity of these tumors it should be taken into consideration in the differential diagnosis of every adrenal tumor. Complete surgical excision is the treatment of choice, adding systemic chemotherapy as adjuvant therapy; radiotherapy is reserved as a second line after excision of recurrences if there are.

Adrenal Gland Neoplasms↗

PubMed2004

[Paratesticular leiomyosarcoma. Review and update].

OBJECTIVES: To present one case of paratesticular leiomyosarcoma, a rare tumor which has been reported in 5 cases only in our country. To review the management of this type of tumor. METHODS: A 73-year-old male presenting with a 4 cm mass adjacent to the right testicle underwent excision of the mass, spermatic cord and testicle through an inguinal approach. RESULTS: The tumor was classified as a grade 3 leiomyosarcoma, with positive immunohistochemical staining for desmin and smooth muscle actin. After this pathology report we did not consider adjuvant oncological treatment. Tumor relapse has not appeared so far. CONCLUSIONS: Radical surgery is the only feasible and successful treatment for paratesticular sarcomas, with the exception of rabdomyosarcoma, because they are radio and chemoresistant. The inguinal approach is the ideal and obligatory one, including excision of the spermatic cord and adjacent testicle. Long-term periodic follow-up visits are mandatory because relapses may occur even long time after diagnosis. In case of relapse, surgery is again the only tool we have to control this type of tumor. Currently radiotherapy is recommended in cases of local recurrence after surgery. 5-year survival rates are around 75%, and 10-year 50%.

Aged↗

PubMed2003

[Foamy carcinoma of the prostate].

OBJECTIVES: We report the first case of prostatic foamy gland carcinoma in the Spanish literature. METHODS: Case of a 69-year-old male who consulted for PSA elevation up to 101 ng/ml. Transrectal ultrasound showed a heterogeneous gland with a hipoechogenic area in the right lobe and possible capsular disruption. Six ultrasound guided needle biopsies were performed. The samples from the right lobe were reported as Gleason 6 foamy cell prostatic adenocarcinoma. RESULTS: Prostatic foamy cell carcinoma is a rare tumor, and so are its bibliographic references. Its cells lack of prominent nucleus and nucleoli. They show a plentiful and xanthomatous cytoplasm, with abundant intracytoplasmic pink secretions characteristically. It may be mistaken with low grade adenocarcinomas, and it is essential to differentiate it from the clear cell prostatic adenocarcinoma, prostatic adenosis, and even from benign prostatic hyperplasia. It usually has an intermediate grade, with a Gleason score greater than 4.

Adenocarcinoma↗

PubMed2003

[Bilateral renal solitary fibrous tumor].

OBJECTIVES: We report the first case of bilateral renal solitary fibrous tumor diagnosed in a patient suffering from tuberous sclerosis. METHODS: From the bibliographic review, only 15 cases of solitary fibrous tumor have been described in the kidney. We did not find any case of simultaneous bilateral involvement. We did not find any case described in a patient with tuberous sclerosis either, as the present case, being a 51-year-old female with presenting with a big abdominal mass arising from the left kidney (25 cm) and another 2 cm mass in the right kidney. CONCLUSIONS: We emphasize the extreme rarity of this tumor in the kidney. It has benign characteristics and behavior, and good prognosis, but requires surgical treatment to obtain a proper histopathologic diagnosis, based on immuno-histochemical studies.

Female↗

PubMed2003

[Testicular leukemic infiltration].

OBJECTIVES: To remind that despite its low incidence, leukemic relapse in the testicles worsens the prognosis of this haematopoietic neoplasia. METHODS/RESULTS: We report the case of a 20-year-old male suffering from acute lymphoblastic leukemia in complete remission after induction and maintenance treatment, who suffered a leukemic relapse in both testicles. Diagnosis was made by ultrasound and confirmed after bilateral testicular biopsies. The patient died due to fungal infection after new treatment with systemic chemotherapy and bone marrow transplantation. CONCLUSIONS: It is necessary to suspect the existence of leukemic cells within the testicles in patients with this disease, mainly acute lymphoblastic leukemia, who present with acute testicular symptoms. Testicular biopsy confirms the diagnosis. Treatment is systemic, with testicular radiation to eradicate the leukemic reservoir. Despite the achievement of local disease control, this situation worsens the prognosis.

Adult↗

PubMed2003

[Urachal cyst. Current status].

OBJECTIVES: We report one case of urachus diverticulum. It is very rare in adults so that the level of diagnostic suspicion is low. METHODS: 50-year-old male without history of urologic diseases who presented with recurrent urinary tract infections over a two-year period. There were not findings on physical examination. Abdominal ultrasound showed a 3 x 2 cm cystic image with internal echoes on the bladder dome. CT scan confirmed the cystic lesion which thickened the bladder wall at the dome. The patient underwent surgery for the excision of a suspected urachal cyst. RESULTS AND CONCLUSIONS: In order of frequency, the 4 types of urachal congenital abnormalities are: permeable urachus (50%), urachal cyst (30%), urachal sinus (15%), and urachal diverticulum (5%). The indication of surgery comes from the possibility of infection and malignant transformation; the cyst should be excised with a bladder dome cuff due to the risk of existence of urachal remnants at that level and their potential to degenerate to adenocarcinoma.

Humans↗

PubMed2003

[Prostatic ductal carcinoma].

OBJECTIVES: We presented one case of prostatic adenocarcinoma of ductal origin, known as endometrial adenocarcinoma before. The first case was published in 1967 by Mellicow. Since then we could only recover 8 cases by spanish authors. METHODS/RESULTS: 61-year-old patient presenting with urethral bleeding, PSA 12 ng/cc, and an exophytic urethral mass. Histology was compatible with ductal adenocarcinoma of the cribiform type. Radical prostatectomy was carried out with good outcome at six months follow up. CONCLUSIONS: Prostatic ductal adenocarcinoma is a rare tumor, accounting for 0.2-5% of prostatic tumours. Its behaviour is variable, similar to the acinar cell type. Strikingly, there are scarce references to this tumor type; accordingly to the statistics of incidence it should have been referred more often, which would help to its study in terms of outcomes, treatment, and prognosis.

Carcinoma, Ductal↗

PubMed2002

[Hyperdense renal cyst].

OBJECTIVE: We update the diagnostic criteria for renal cystic masses, emphasising in the clinical entity known as hyperdense renal cyst. METHODS: We report the case of a male patient who presented with an atypical left renal cyst. Radiological examinations (US and CT) were performed. A description of renal cyst classification is made. We review the diagnostic criteria for hyperdense renal cyst using the iconography from this case and also its therapeutic approach. RESULTS: An image compatible with left simple renal cyst was found on ultrasound. A CT scan study showed an homogeneous mass with a high attenuation value, non vascular in nature, which complies with all diagnostic criteria for hyperdense renal cyst. CONCLUSIONS: Hyperdense renal cyst is a simple cyst which has suffered bleeding or infection. Diagnosis is made by CT scan and it does not require treatment.

Adult↗

PubMed2002

[Urinary endometrioma].

OBJECTIVES: To analyze the series of cases of endometriosis with urologic involvement reported in our country. METHODS/RESULTS: We found a total of 26 cases of endometriosis including our case, 15 affected bladder and 11 ureter. Independently of ureteral or bladder location, the treatment performed varied, from transurethral resection and laser to cystectomy in cases involving bladder, from segmental ureterectomy with ureteral reimplantation to nephrectomy in ureteral cases. CONCLUSIONS: Surgery is the definitive solution for urinary tract endometriomas. The definitive treatment of endometriosis must be done by gynecologists, by means of hormonal and surgical treatment depending on age, severity and location of the lesions, patient's wishes for future pregnancies, and tolerance to hormone therapy.

Adult↗