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Vadim Y Soloviev

Publications and source records attributed to Vadim Y Soloviev.

4 recordsLinked to original sources

Consideration of a spread-out source in problems of near-infrared optical tomography.

When the light propagates in media where absorption is not negligible and/or scattering is weak, a contribution to the energy density coming from ballistic photons cannot be neglected. A point source effectively spreads out over a scattering volume and its spatial distribution is described by the source function. We consider a boundary value problem of light propagation in half-space for such a source on the basis of the telegraph equation. A solution is found by convolution of Green's function with the source function. The final result shows a significant difference in the behavior of the radiant energy density between the solution obtained for a distributed source and the diffusion approximation. Our results agree well with the Monte Carlo simulations over a broad range of scattering and/or absorption conditions. The obtained results are of practical importance in luminescence optical tomography because an erroneous shape of the energy density function may lead to an incorrect estimate of the light source depth after image reconstruction. The range of applications of the diffusion approximation is also discussed.

Algorithms↗

Dynamically adaptive mesh refinement technique for image reconstruction in optical tomography.

A novel adaptive mesh technique is introduced for problems of image reconstruction in luminescence optical tomography. A dynamical adaptation of the three-dimensional scheme based on the finite-volume formulation reduces computational time and balances the ill-posed nature of the inverse problem. The arbitrary shape of the bounding surface is handled by an additional refinement of computational cells on the boundary. Dynamical shrinking of the search volume is introduced to improve computational performance and accuracy while locating the luminescence target. Light propagation in the medium is modeled by the telegraph equation, and the image-reconstruction algorithm is derived from the Fredholm integral equation of the first kind. Stability and computational efficiency of the introduced method are demonstrated for image reconstruction of one and two spherical luminescent objects embedded within a breastlike tissue phantom. Experimental measurements are simulated by the solution of the forward problem on a grid of 5x5 light guides attached to the surface of the phantom.

Algorithms↗

Mesh adaptation technique for Fourier-domain fluorescence lifetime imaging.

A novel adaptive mesh technique in the Fourier domain is introduced for problems in fluorescence lifetime imaging. A dynamical adaptation of the three-dimensional scheme based on the finite volume formulation reduces computational time and balances the ill-posed nature of the inverse problem. Light propagation in the medium is modeled by the telegraph equation, while the lifetime reconstruction algorithm is derived from the Fredholm integral equation of the first kind. Stability and computational efficiency of the method are demonstrated by image reconstruction of two spherical fluorescent objects embedded in a tissue phantom.

Algorithms↗

Phosphorescence lifetime imaging in turbid media: the inverse problem and experimental image reconstruction.

Three-dimensional phosphorescence lifetime imaging is a novel method for the mapping of oxygen concentration in biological tissues. We present reconstruction techniques for recovering phosphorescent objects in highly scattering media based on the telegraph equation and two regularization methods, i.e., the Tikhonov-Phillips regularization and the maximum entropy method. Theoretical results are experimentally validated, and the reconstructed images of phosphorescent objects rendering oxygen maps in a layer are presented.

Biological Phenomena↗