Radioprotectants: adding quality of life to survivorship?
OBJECTIVES: To explore the use of radioprotectants in oncology and their affect on quality of life (QOL). DATA SOURCES: Textbooks, manuals, and journals in radiation oncology and cancer nursing. CONCLUSION: Many studies have shown that the use of amifostine has decreased the intensity and severity of treatment-related side effects as well as improving QOL. However, more research is needed in the development of newer agents and refining older agents. IMPLICATIONS FOR NURSING PRACTICE: With the advent of combined modality treatments, overall response and survival benefit has increased as well as enhanced toxicities affecting one's QOL. Agents such as radioprotectants and advances in supportive care have assisted in minimizing treatment-related side effects. Strides toward providing quality, compassionate care remain the goal of oncology nurses, while enhancing the QOL for cancer patients.