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Biomedical subjects

Vaqar Bari

Publications and source records attributed to Vaqar Bari.

13 recordsLinked to original sources
PubMed2006

Role of focused appendiceal computed tomography in clinically equivocal acute appendicitis.

OBJECTIVE: To determine the accuracy of FACT (focused appendiceal computed tomography) in evaluation of acute appendicitis. METHODS: The study was conducted in Aga Khan University Hospital, Karachi, over a period of one year. Sixty-three patients with clinically equivocal acute appendicitis underwent thin-section non-enhanced helical CT. Axial scans were obtained in a single breath hold from L2 vertebral level to the pubic symphysis with 5-mm collimation and a pitch of 1.5. All scans were obtained without oral, intravenous, or rectal contrast material. Criteria for diagnosis of acute appendicitis included an enlarged appendix (>6 mm diameter) and periappendiceal inflammation. Final diagnoses were established with the results of surgical or clinical follow-up. RESULTS: There were 21 true-positive diagnoses, 38 true-negative diagnoses, no false-positive diagnoses, and 2 false-negative diagnoses, which yielded a sensitivity of 91% and a specificity of 100%. CONCLUSION: Non-enhanced FACT is a highly accurate problem solving technique in clinically equivocal cases of acute appendicitis.

Acute Disease↗
PubMed2006

Evaluation of erectile dysfunction with color Doppler sonography.

OBJECTIVE: To assess the role of Color Doppler Sonography in the evaluation of erectile dysfunction. METHODS: A cross-sectional study was conducted at the Radiology Department, Aga Khan University Hospital Karachi from 5-6-2002 to 2-9-2003. All consecutive patients presenting with erectile dysfunction and undergoing penile color Doppler evaluation with injection PGE1 20 mcg were included in this study. RESULTS: A total of 70 patients with an age range of 24-70 years (mean 41 +/- 12.25 years) were included in the study. A normal response was noted in 45 (psychogenic) cases. Vasculogenic causes were observed in 23 patients, 12 with arterial insufficiency and 11 with venous leak. Peyronie's disease was diagnosed in 2 patients. CONCLUSION: Color Doppler evaluation of erectile dysfunction is an effective method for differentiating psychogenic and vasculogenic causes of erectile dysfunction.

Adult↗
PubMed2005

Multiple parameters in the diagnosis of ectopic pregnancy.

OBJECTIVE: To determine the role of emergency ultrasound examination in the diagnosis and management of ectopic pregnancy. METHODS: A descriptive study done at the Radiology Department, Aga Khan University Hospital, Karachi from January 1999 to December 2000 using observational facts by non-probability convenient sampling method. Seventy one patients who presented with acute symptoms in early pregnancy, were subjected to emergency pelvic ultrasound. Both transabdominal and transvaginal ultrasound were done in 52 patients while in 19 patients only transabdominal ultrasound was performed. Serum Beta hCG levels, of all patients were greater than 1500 iu/ml. RESULTS: Ultrasound correctly identified ectopic pregnancy in 71 patients. Ultrasound diagnosis included live embryo in six patients, adnexal mass with pelvic fluid in 54 patients, extrauterine gestational sac in 4 patients and pelvic fluid without adnexal mass in 7 patients. There was no indeterminate ultrasound scan, resulting in 100% specificity and sensitivity. CONCLUSION: The use of multiple parameters in the diagnosis of ectopic pregnancy resulted in 100% sensitivity and specificity.

Adult↗
PubMed2005

Role of computed tomography in acute pancreatitis and its complications among age groups.

OBJECTIVE: To determine value of CT scan in diagnosis of acute pancreatitis, its complications and to correlate with severity among different age groups. METHODS: The study was carried out from August 2001 to August 2002 at the Radiology Department, Aga Khan University Hospital. A total of 40 patients (33 male and 7 female) with age range from 16-71 years were divided in three groups. Group I was less than 40 years (12 patients), Group II was between 40-60 years (17 patients), and Group III was more than 60 years (11 patients). CT scans were assessed for pancreatic necrosis and its complications. CT Severity Index (CTSI) was calculated according to Balthazar's method. RESULTS: In 17 patients with mild pancreatitis, 5 had necrosis involving one-third of pancreas. In 13 patients with severe pancreatitis, 8 had necrosis involving more than half of the pancreas and 5 had necrosis involving half of the pancreas. No significant correlation was demonstrated between moderate pancreatitis and degree of necrosis. Thirty patients had complications, 8 had mild CTSI, 9 had moderate CTSI and 13 patients had severe CTSI. CONCLUSION: The study demonstrated a relationship between CTSI and severity of pancreatic damage and incidence of complications.

Adolescent↗
PubMed2004

Magnetic resonance imaging in the diagnosis and local staging of primary bone tumors.

OBJECTIVE: To evaluate relationship of magnetic resonance (MR) imaging in the diagnosis and local staging of primary bone tumors with histopathological and surgical outcome. DESIGN: Cross-sectional comparative study. PLACE AND DURATION OF STUDY: Radiology Department, The Aga Khan University Hospital, Karachi from December 1999 to March 2002. SUBJECTS AND METHODS: Thirty patients suspected of having primary bone tumors were selected. MRI scans were evaluated for local staging including intramedullary tumor length, cortical, soft tissue, neuro-vascular, joint and epiphyseal involvement. MR staging was compared with surgical and pathological staging and MR diagnosis with histopathological diagnosis considering benign and malignant tumors and specific diagnosis. RESULTS: The study included 30 patients with age ranging from 5 - 75 years (mean 30.1 years). Twenty-three patients had malignant and 7 benign tumors. On MRI, 25 tumors were characterized as malignant and 2 tumors were false positive for malignancy. CONCLUSION: MR imaging proved to be accurate in local staging of bone tumors and determination of the extent of disease in benign tumors.

Adolescent↗
PubMed2004

Mesenteric panniculitis.

Mesenteric panniculitis is a rare condition of unknown etiology that causes inflammation of the adipose tissue in the mesentery. We describe a case in which mesenteric panniculitis was diagnosed on the basis of imaging and resolved spontaneously.

Aged↗
PubMed2004

Ultrasound differentiation of benign versus malignant solid breast masses.

OBJECTIVE: To determine the reliability of ultrasonographic features in differentiating benign from malignant solid breast masses. DESIGN: Descriptive, analytical study. PLACE AND DURATION OF STUDY: Radiology Department, Aga Khan University Hospital, Karachi from July 2000 to June 2002. SUBJECTS AND METHODS: One hundred solid breast masses in females with a tissue diagnosis available were reviewed. Two radiologists reviewed the sonographic features of masses without knowledge of clinical history or histologic examination results. Ultrasound features were corrected later with histologic features to determine the reliability of the former in benign or malignant nature of nodules. RESULTS: Ultrasound features that most reliably characterize masses as benign were a round or oval shape, circumscribed margins and a width to antero-posterior (AP) dimension ratio greater than 1.4. Features that characterized masses as malignant included irregular shape, spiculated margins and width to antero-posterior (AP) dimension ratio of 1.4 or less. If these three most reliable criteria had been strictly applied by the primary reporting radiologist, the overall cancer biopsy yield would have increased. CONCLUSION: The data confirms that certain ultrasound features can help differentiate benign from malignant masses. However, practice and interpreter variability should be further explored before these criteria are applied to defer biopsy of solid masses.

Adult↗
PubMed2004

Damage control laparotomy for exsanguinating penetrating abdominal trauma.

Damage control, defined as initial control of haemorrhage and contamination with intra-peritoneal packing and rapid closure, allows the resuscitation to normal physiology in the intensive care unit and subsequent definitive re-exploration. A case of penetrating abdominal trauma with extensive hepatic, interior vena cava and pancreatico-duodenal injuries, was managed on the principles of damage control on the first laparotomy and definitive procedure of pancreaticoduodenectomy was delayed and performed after 48 hours.

Abdominal Injuries↗
PubMed2004

Ultrasound in the diagnosis and management of intrauterine growth retardation.

OBJECTIVE: To evaluate the value of ultrasound in the diagnosis and management strategies of intrauterine growth retardation. DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: Radiology Department, Aga Khan University Hospital, Karachi, from April 1998 to August 1999. PATIENTS AND METHODS: The study population comprised of 206 subjects evaluated for suspected intrauterine growth retardation. Grey scale as well as Doppler ultrasound findings were evaluated and compared against post-natal outcome. RESULTS: One hundred and eight out of 206 subjects showed positive imaging results with 40 false positive and 20 false negative subjects. The sensitivity, specificity, positive predictive and negative predictive values were 77.8%, 66.1%, 55.6%, and 45.1% respectively. Forty subjects showed false positive results on imaging (low biophysical profile score and Grey scale biometry discrepancy) while 20 of the subjects showed false negative results (normal on US imaging) when compared with postnatal neonatal body weight criteria. Twenty-two subjects had oligohydramnios with amniotic fluid index below 5 percentile for their respective gestational ages (20%) out of 108. CONCLUSION: Obstetric and Doppler ultrasound is an accurate method for diagnosis and management of fetal growth retardation.

Adolescent↗
PubMed2003

Unenhanced helical CT scan for the investigation of acute ureteral colic.

Unenhanced helical CT is presently considered a superior imaging technique for investigating acute urinary colic compared to intravenous urography and ultrasound. It was introduced in Pakistan around the year 2000 and is in the process of being acknowledged as the first line investigation in emergency departments. We have discussed the advantages and the disadvantages of the technique, and have compared it with other imaging modalities.

Acute Disease↗
PubMed2003

Accuracy of magnetic resonance imaging in the knee.

OBJECTIVE: To determine the accuracy of magnetic resonance imaging (MRI) in the assessment of various knee disorders in comparison with arthroscopic findings and pathologic diagnosis. DESIGN: A retrospective and comparative study. PLACE AND DURATION OF STUDY: Radiology Department, Aga Khan University Hospital, Karachi, from 01-12-1996 to 30-06-2000. PATIENTS AND METHODS: Fifty-six subjects (36 males and 20 females), included in this study, had abnormal findings on MRI, which were correlated with arthroscopic findings in 50 cases and pathological diagnosis in 6 cases. Plain X-rays were available in all cases. RESULTS: The sensitivity, specificity and accuracy for MRI of the menisci and cruciate ligaments were as follows: medial meniscus pathologies 87% sensitivity, 94% specificity and 92% accuracy; lateral meniscus pathologies 92% sensitivity, 89% specificity and 90% accuracy; anterior cruciate ligament injuries 95% sensitivity, 96% specificity and 96% accuracy and posterior cruciate ligament injuries 100% sensitivity, 98% specificity and 98% accuracy. Pathological diagnosis was available in 6 cases. MR imaging suggested the diagnosis of tuberculosis and metastases as well as mapped out the extent of osteogenic sarcoma, fibromatoses and rhabdomyosarcoma. CONCLUSION: This study confirms that MR imaging of the knee is highly sensitive, specific, and accurate.

Adolescent↗