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Biomedical subjects

Vasumathy Vedantham

Publications and source records attributed to Vasumathy Vedantham.

At least 19 recordsLinked to original sources

Diffuse unilateral subacute neuroretinitis with unusual findings.

PURPOSE: To report two cases of diffuse unilateral subacute neuroretinitis (DUSN) with unusual findings. DESIGN: Observational and interventional case series. METHODS: Two patients with DUSN were found to have the unusual findings of a large live worm in one eye and macular cyst in the other. Both patients underwent fundus fluorescein angiography and optical coherence tomography. RESULTS: Photocoagulation to the worm was performed in one patient; the other received a course of oral albendazole. Both remained stable over six months of follow-up. CONCLUSIONS: We report a case of DUSN due to a worm, the large size of which suggests it to be different from the usual reported causative agents. We also report macular cyst as an associated finding in DUSN.

Acute Disease↗

Clinico-microbiological profile and visual outcomes of post-traumatic endophthalmitis at a tertiary eye care center in South India.

PURPOSE: To analyze the clinical and microbiological characteristics of eyes with post-traumatic endophthalmitis and factors influencing the visual outcomes in these cases. METHODS: We performed a retrospective chart analysis of the clinical and microbiological data of 97 consecutive patients with post-traumatic endophthalmitis presenting to a tertiary eye care hospital in South India. RESULTS: Thirty-nine (40.2%) cases were culture-positive, gram-positive cocci (n=24/42, 57.1%) being the commonest isolates. Staphylococcus epidermidis and Pseudomonas aeuruginosa were the commonest single isolates (n=10; 23.8%). Majority of the organisms were sensitive to chloramphenicol (n=27) or ciprofloxacin (n=26). Susceptibility to vancomycin (n=3) and amikacin (n=4) was poor. Cases with negative cultures at presentation were more likely to have improvement in visual acuity compared with culture-positive cases (on multivariate analysis, OR: 3.2, 95% CI: 1.1, 9.0). CONCLUSIONS: In this series of post-traumatic endophthalmitis, a high prevalence of resistance of the culture isolates to vancomycin and amikacin was observed.

Adolescent↗

Atypical manifestations of acute posterior multifocal placoid pigment epitheliopathy.

We report four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE) with atypical features which were unilaterality, serous detachment of the neurosensory retina, retinal vasculitis and papillitis. All patients responded well to oral corticosteroids. We suggest that systemic corticosteroids could be useful in selected cases of APMPPE with atypical clinical features.

Administration, Oral↗

Intravitreal injection of triamcinolone acetonide for diabetic macular edema: principles and practice.

Diabetic retinopathy is fast emerging as a leading cause of newly diagnosed legal blindness amongst the working population. Macular edema, as it is commoner, accounts for more vision impairment than neovascular proliferation in diabetic patients. Laser photocoagulation, which is the standard treatment of macular edema, is associated with significant complications and an improvement in visual acuity is unsatisfactory. Intravitreal injection of corticosteroids (especially triamcinolone acetonide) is an emerging treatment modality in the management of diabetic macular edema. This article presents an overview of the principles, technique and complications associated with this procedure.

Diabetic Retinopathy↗

Optical coherence tomography in Best's disease: an observational case report.

PURPOSE: To report the optical coherence tomographic (OCT) findings in a case of Best's disease. DESIGN: Observational case report. METHODS: Optical coherence tomography was carried out to understand the pathogenesis of Best's disease in a 13-year-old girl. RESULTS: Optical coherence tomography demonstrated that the lipofuscin accumulated in a cystic space underneath the retinal pigment epithelium in the "pseudohypopyon stage" of Best's disease. It also demonstrated the disruption of the photoreceptors in the "scrambled egg" stage. CONCLUSIONS: These new OCT findings could explain the retention of good visual acuity in the "pseudohypopyon stage" and the loss of visual acuity in the "scrambled egg" stage of Best's disease.

Adolescent↗

Correspondence.

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Fovea Centralis↗

Premacular haemorrhage associated with arteriovenous communications of the retina induced by a valsalva-like mechanism: an observational case report.

A 26-year-old woman presented with sudden defective vision in the right eye following lifting a heavy bucket of water. Examination showed a dense premacular subhyaloid haemorrhage associated with arteriovenous communications of the retina (AVCRs). Spontaneous absorption of the premacular haemorrhage with consequent improvement in the visual acuity was seen after two months. The possible aetiopathogenesis of the case is also discussed.

Adult↗