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Biomedical subjects

Vignendra Ariyarajah

Publications and source records attributed to Vignendra Ariyarajah.

20 records · Page 2Linked to original sources

Acute pericarditis: diagnostic cues and common electrocardiographic manifestations.

Acute pericarditis (AP) is basically a clinical diagnosis. Although specific electrocardiographic (ECG) manifestations may indeed point to its diagnosis, sole reliance on such findings in isolation of the clinical setting, however, is often the common pitfall that could lead to a misguided diagnosis. We briefly review the anatomy of the pericardium and the pathophysiology of pericarditis to highlight common signs and symptoms as well as clinical findings that may assist in the diagnosis of AP. We also feature the characteristic evolution of its ECG manifestations and point out some of its typical and atypical features to help better differentiate AP from commonly confused conditions.

Acute Disease↗

Prevalence of interatrial block in the Program of All-Inclusive Care for the Elderly (PACE).

Interatrial block (IAB) (P wave > or =110 milliseconds) is a potent correlate of atrial tachyarrhythmias, left atrial electromechanical dysfunction, and embolism. IAB has been demonstrated to be highly prevalent in the general hospital population, but no investigation has addressed this in the elderly community outside the hospital. We appraised the prevalence of IAB in a service of the Program of All-Inclusive Care for the Elderly (PACE), the Elder Service Plan (ESP). Of the 202 ESP members in Worcester, MA, 167 (ages 61-103 years; female 81.4%) who had current 12-lead electrocardiograms were evaluated for IAB, and an age-based comparison was made between those with and without IAB. Of those patients with current electrocardiograms, 148 (88.6%) showed sinus rhythm and 72 (48.6%) depicted IAB: 20% in patients aged 60-69 years, 39.5% aged 70-79 years, 56.8% aged 80-89 years, and 50% in those 90 years and older. Given its sequelae of anatomic and pathophysiologic consequences, prompt recognition of IAB in a high-risk group such as that in the PACE community (48.6% prevalence) is important, especially for anticipation of atrial fibrillation and possible embolism.

Age Factors↗