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Vui Heng Chong

Publications and source records attributed to Vui Heng Chong.

16 recordsLinked to original sources

A rare cause of acute upper gastrointestinal bleeding.

Acute upper gastrointestinal bleeding (AUGB) remains a common indication for admissions and is associated with significant morbidity and mortality. Peptic ulcer diseases and varices are the commonest lesions identified during endoscopy. However, endoscopists need to be aware of the rare causes of AUGB, as missing such lesions can potentially be fatal. Rare causes can be missed if they are not looked for systematically during endoscopy. We report a case of AUGB secondary to bullous pemphigoid involving the esophagus in an elderly gentleman presenting with significant blood loss from hematemesis. A review of the English literatures on bullous pemphigoid involvements of the esophagus was carried out and the underlying pathogenesis and management are discussed.

Acute Disease↗

Cervical inlet patch: case series and literature review.

Heterotopic gastric mucosa patch (HGMP) has been reported to occur in various parts of the gastrointestinal system from mouth to anus. Extra-gastrointestinal locations have also been reported. Presence of ectopic gastric mucosa has been associated with complications such as ulceration, bleeding, perforations and malignant transformations. Most complications are probably related to acid production. Meckel diverticulum is the most commonly reported ectopic location. Similarly, esophageal HGMP, also known as cervical inlet patch (CIP), has been increasingly reported. Nonspecific oropharyngeal symptoms are common and thought to be due to laryngopharyngeal reflux. CIP is often missed due to its location in the esophagus, just distal to the upper esophageal sphincter, making endoscopic evaluation difficult. Hence the condition is most likely to be under-reported. This article presents a series of five cases of CIP and discusses the pathogenesis, clinical presentations and management of this interesting entity.

Adult↗

Human immunodeficiency virus and endoscopy: Experience of a general hospital in Singapore.

INTRODUCTION: As the human immunodeficiency virus (HIV) pandemic continues, demand on the endoscopic services will also increase. The aim of the present study was to characterize the characteristics and endoscopic findings of HIV-infected Asian patients. METHODS: Patients with HIV/AIDS who had endoscopy from January 1997 to September 2002 were identified and retrospectively reviewed. RESULTS: There were 125 patients (male, 111; mean age: 43.2 +/- 11 years; mean CD4 count 63 +/- 85/mm(3), range, 1-342/mm(3)) who underwent 181 procedures (upper gastrointestinal endoscopy [UGIE], n = 141; lower gastrointestinal endoscopy [LGIE], n = 40). The median time from diagnosis to endoscopy was 240 days (-660 to 4680 days). For UGIE the main findings were candidiasis, 23.1%; cytomegalovirus esophagitis/ulcers, 11.2%; duodenal ulcers, 8.4%; gastric ulcers, 7.0%; portal-hypertensive-related changes, 6.3%; idiopathic esophageal ulcers, 3.5%; herpes simplex esophagitis/ulcers, 3.5%; and tuberculosis, 2.1%. The CD4 counts were significantly lower in those with opportunistic infections (P = 0.004) but there was no difference between significant and non-significant findings (P = 0.191). For LGIE 35% had endoscopic colitis, 80% of which were non-specific. Significant findings were ileal tuberculosis, n = 3; colon cancer, n = 1; and colonic fistula, n = 1. Ten patients had undergone 16 procedures (UGIE, n = 13; LGIE, n = 3) prior to the diagnosis of HIV/AIDS. They were all male Chinese patients, with positive contact with commercial sex workers (CSW) and had lymphopenia at time of endoscopy. The median time from endoscopy to diagnosis was 180 days (range, 1-660 days). There were no significant differences in age (P = 0.512) and CD4 count at diagnosis (P = 0.066) between patients who had endoscopy before and after diagnosis of HIV/AIDS. Four procedures led to the suspicion of HIV. CONCLUSIONS: Endoscopic findings of symptomatic HIV Asian patients are comparable to those of the West. Universal precautions should always be exercised in all procedures to avoid transmission of disease.

AIDS-Related Opportunistic Infections↗

Iatrogenic biliary stone.

Biliary stone disease is a common disorder, usually associated with stones in the gallbladder, and can cause significant complications. Formations of stone usually occur in the presence of the following factors: abnormalities of the bile constituents, bile stasis, and the presence of nidus for stone formations. Numerous reports exist of foreign bodies (FBs) acting as nidus for stone formations within the biliary system. The FBs reported include surgical sutures, surgical clips, fragments of metal and plastics, ingested materials, and parasites. Surgical clips are reported to be the most commonly reported FBs that induce iatrogenic biliary stones. Surgical clips migration with subsequent stone formation is a well-recognized phenomenon since first used in surgery. Patients typically are first seen with symptoms of biliary obstruction and can be complicated by life-threatening cholangitis. These can occur from days to years after the initial surgical procedures. The underlying mechanism of the way in which FBs-including surgical clips-end up in the biliary system is unknown. Direct introduction during surgery, penetrating injuries, entero-bilio reflux, or erosions with eventual migration into the biliary system have been postulated. Bile-duct injuries, inappropriate clip placements, sub-clinical bile leak, and infections also have been postulated to contribute to clip migration. This Chapter reviews the literature regarding iatrogenic biliary stones as a result of FBs, and discusses the likely mechanisms involved with their migrations, stone formations, clinical presentations, and managements.

Foreign Bodies↗