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Biomedical subjects

W A De Sy

Publications and source records attributed to W A De Sy.

At least 37 records · Page 2Linked to original sources

[A transglandular tunnel in the treatment of hypospadias].

A technique and the results of the creation of a transglandular tunnel for the more aesthetic repair of hypospadias is reported. The tunnel is not trocardisized through the glans but really excised. This reduced considerably the risk of stenosis, as this occurred only 9 times in 112 cases. In only three of them a reoperation was necessary. Sensibility of the glans remains normal after the operation while the appearance is a nearly normal.

Humans↗

Enterocystoplasty after cystoprostatectomy for bladder cancer. Time-saving technical modifications.

Enterocystoplasty, to construct a functional and continent bladder in male patients following cystoprostatectomy, can be simplified and shortened by some modifications. Partial pubectomy will allow a precise and bloodless section of the membranous urethra preserving the external sphincter and a watertight anastomosis with 10 to 12 stitches between the urethra and the intestinal bladder. Use of automatic intestinal suture devices. Passing the ureteral stents through stab wounds in the intestinal wall and out to the skin. An easy method for bringing the urethral catheter in the right horn of the intestinal bladder. These modifications will reduce the operating time to seven hours.

Humans↗

Intracavernous injection of noradrenaline to interrupt erections during surgical interventions.

Injection of a small dose of noradrenaline in one corpus cavernosum caused quick detumescence in 10 children and 7 adults with disturbing peroperative erections. The mode of administration is simple, and complications have not appeared. As this therapy has always been effective and avoids the need for deeper anesthesia, we dare to recommend it as first choice treatment for peroperative erections.

Adult↗

Antireflux in adults: a long-term follow-up.

The long-term results after antireflux operation in 47 adults are presented. Reflux was eliminated in all but 3 cases. Preoperatively most patients complained of urinary tract infection with or without fever, but sometimes investigation for hypertension or urolithiasis also led to the diagnosis. Postoperatively 70% of the patients are free of symptoms and infection. Renal scarring in pyelonephritic patients seems to stop after intervention. In all patients with a normal preoperative creatinine level, this level stays normal after the intervention. However, in 6 of 7 patients with a creatinine level of greater than 1.5 mg% before operation, the intervention could not stop the evolution toward terminal renal failure.

Adolescent↗

Results of urometabolic evaluation in 127 patients with renal calculous disease.

One hundred twenty-seven selected stone formers were evaluated. With the simple ambulatory tests proposed by Pak for metabolic screening and a complete urologic evaluation an anomaly was found in more than 90 per cent of the cases. The patients were divided into three groups: (1) patients operated on for staghorn stones; (2) patients with episodes of spontaneous stone eliminations or young people with only one stone episode; and (3) patients operated on for stone disease. No significant differences were noted except for the occurrence of urinary tract infection and for struvite and calcium oxalate occurrence in the different groups. Urinary tract infection combined with a metabolic disorder appear to make the evolution from small kidney stone to staghorn stone a reality.

Adult↗

Correlation between the findings of a clinical neurological examination and the urodynamic dysfunction in children with myelodysplasia.

Clinical neurological findings in 47 children with lumbosacral myelodysplasia did not correlate well with the existing dysfunction of the lower urinary tract as diagnosed by urodynamic studies. The level of intact skin sensation, and the presence or absence of bulbocavernosus and anal reflexes could not significantly predict the function of the detrusor muscle, proximal urethra and striated urethral sphincter. Therefore, one should not rely on a clinical neurological examination to outline the urological management in such patients.

Adolescent↗

Evaluation of different methods of bladder drainage used in the early care of spinal cord injury patients.

In a series of 115 spinal cord injury patients four different methods of bladder drainage were used mainly during spinal shock. That is a) suprapubic fine bore cystostomy, b), indwelling Foley catheter, c) intermittent catheterisation; and d) both last methods consecutively. The methods of bladder drainage used did not influence the number of patients becoming catheterfree but determined significantly the length of period before patients became catheterfree. Patients on intermittent catheterisation had the shortest time from injury to established micturition. Patients on intermittent catheterisation and on cystostomy had few complications but in those patients treated with an indwelling Foley catheter the complication rate was high.

Adolescent↗

Captopril: a protective agent in renal warm ischemia in rats.

Captopril, an angiotensin-converting enzyme inhibitor, was used as a protective agent before and after 90 min of renal warm ischemia in rats. At a dose of 1 mg/kg, it was able to lower the postoperative serum creatinine values significantly (from 6.3 to 2.5 mg% on the 2nd postoperative day) in unilaterally nephrectomized animals. Increasing the dose to 4 and 8 mg/kg or combining captopril with hypertonic mannitol (10 ml/kg of a 15% aqueous solution) did not improve these figures significantly. The same magnitude of protection was obtained when captopril was given either before or just after the ischemia. In terms of mortality the differences among unprotected and protected groups were very important: only 6 of 24 unprotected animals survived the 5th postoperative day while 42 of 44 protected animals survived.

Animals↗

[Balanopreputial hypospadias].

Magpi's technique is described. It is an excellent procedure for the cure of the majority of cases of coronal or just subcoronal hypospadias, but its use is contra-indicated in the presence of a very large meatus, a thin, transparent, distal urethra, or a deeply grooved glans. In these cases, other techniques are required.

Follow-Up Studies↗