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Biomedical subjects

W A Ferrante

Publications and source records attributed to W A Ferrante.

At least 19 recordsLinked to original sources
PubMed1992

Gallstone disease. Pathophysiology, epidemiology, natural history, and treatment options.

In 1991, only symptomatic gallstones should be treated. The treatment of choice for all gallstones continues to be surgical removal. Except for stones in the common bile duct, which are amenable to removal by endoscopic papillotomy, nonsurgical treatment of gallstones should be investigated further before it can have widespread applicability. The major challenge in the future may be medical prevention of gallstone formation in susceptible individuals. Laparoscopic cholecystectomy seems to have moved to the forefront of surgical therapy in patients who are candidates for the procedure.

Adolescent↗
PubMed1990

Hepatic hemangioma with normal angiograms. Three case reports.

Three cases of symptomatic cavernous hemangioma of the liver are reported. All three patients have normal angiograms. A review of the literature shows that the diagnosis of hemangioma may be made noninvasively with a high degree of accuracy. Technetium Tc 99m-labeled red blood cell scanning is very specific, while dynamic computed tomography may be more sensitive for small lesions. A combination of the two modalities makes the diagnosis in greater than 90% of cases. Magnetic resonance imaging is also sensitive and specific. Angiography, as shown in these cases, may not only be questionably indicated, but may be misleading. The treatment for symptomatic lesions is resection, and secondary alternatives are discussed.

Adult↗
PubMed1983

Secondary achalasia: association with adenocarcinoma of the lung and reversal with radiation therapy.

A case of secondary achalasia associated with adenocarcinoma of the lung is presented. Manometric studies before, during, and at the conclusion of radiation therapy demonstrated a return of orderly peristalsis, decrease in the elevated lower sphincter pressure, and a return of normal relaxation coincident with resolution of symptoms of dysphagia. The association with adenocarcinoma of the lung and resolution with radiation therapy alone have not been previously reported in secondary achalasia.

Adenocarcinoma↗
PubMed1980

Malabsorption in jejunal diverticulosis treated with resection of the diverticula.

Patients with jejunal diverticula usually are asymptomatic unless bacterial overgrowth within the diverticula is sufficient to cause vitamin B12 deficiency, by direct uptake of the vitamin by the bacteria, or malabsorption resulting from bacterial deconjugation of bile salts and impaired lipid digestion. The administration of broad-spectrum antibiotics usually constitutes effective treatment that suppresses bacterial flora, with surgery reserved for complications such as hemorrhage, perforation, and abscess formation, and acute or chronic intestinal obstruction. Our patient had many diverticula, and two courses of antibiotics failed to provide prolonged relief of symptoms. After surgical exploration to exclude the presence of partial intestinal obstruction or infiltrating disease of the terminal ileum, the segment of jejunum bearing diverticula was resected. Since operation the patient has remained asymptomatic, which suggests that in certain patients, even with many diverticula, surgical exploration and excision of the diverticula may be curative.

Aged↗
PubMed1976

Esophageal ulcers associated with tetracycline therapy.

Esophageal ulceration has rarely been reported secondary to medicinal agents. we have treated three patients with esophageal ulceration associated with the ingestion of tetracycline or its derivative doxycycline. In light of the strong temporal relationship between taking the capsules and the onset of the esophageal ulceration, we believe that the capsules were the cause of the ulcers. We therefore recommend an alternative agent to tetracycline or doxycycline, if possible, for patients with any esophageal obstructive element. We also recommend that patients be cautioned not to take these drugs within one hour of going to bed.

Acne Vulgaris↗
PubMed1976

Hepatoma occurring two decades after hepatic irradiation.

Hepatoma has been related to chemical, dietary, metabolic, infectious, and genetic factors. therapeutic hepatic irradiation has never been associated with hepatoma. A case of hepatocellular carcinoma is presented that occurred two decades after radiotherapy for presumed hepatic hemangioma. Radiation-related liver disease is discussed in general, with emphasis placed on radiation hepatocarcinogenesis.

Carbon Tetrachloride Poisoning↗