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Biomedical subjects

W A GILLESPIE

Publications and source records attributed to W A GILLESPIE.

At least 19 recordsLinked to original sources
PubMed1964

BACTERIOLOGICAL COMPLICATIONS FROM THE USE OF URETHRAL INSTRUMENTS: PRINCIPLES OF PREVENTION.

Guidance by bacteriologists and changes in theatre and ward disciplines have greatly improved the results of urological surgery in recent years. The most noteworthy successes have been in treatment of chronic retention with renal failure, and in prevention of the bacteraemia which may occur following removal of the post-operative catheter or the passage of an instrument to dilate a stricture. It is hoped that safer urethral instrumentation may also reduce the incidence of chronic pyelonephritis.

Anuria↗
PubMed1964

BACTERIAL ENDOCARDITIS DUE TO AN ACTINOBACILLUS.

A case of subacute bacterial endocarditis due to Actinobacillus actinomycetemcomitans followed dental extraction under penicillin cover. Isolation of the organism was only achieved by incubating blood cultures in a CO(2)-enriched atmosphere. The patient was successfully treated with streptomycin.

Actinobacillus↗
PubMed1961

Chemical disinfection in the prevention of infection in hospital.

Much cross-infection can be prevented by using chemical disinfectants to reduce the numbers of pathogens in sources such as superficial lesions and carrier sites, and by interrupting routes of spread. Examples are given to show the value of using disinfectants in the light of epidemiological knowledge.

Cross Infection↗
PubMed1961

Disinfection of woollen blankets in steam at subatmospheric pressure.

Blankets may be disinfected in steam at subatmospheric pressures by temperatures below boiling point inside a suitably adapted autoclave chamber. The chamber and its contents are thoroughly evacuated of air so as to allow rapid heat penetration, and steam is admitted to a pressure of 10 in. Hg below atmospheric pressure, which corresponds to a temperature of 89 degrees C. Woollen blankets treated 50 times by this process were undamaged. Vegetative organisms were destroyed but not spores. The method is suitable for large-scale disinfection of blankets and for disinfecting various other articles which would be damaged at higher temperatures.

Disinfection↗
PubMed1960

The diagnosis, epidemiology and control of urinary infection in urology and gynaecology.

In a study of the urine after urological operations, quantitative bacteriological criteria for the diagnosis of infection were determined. The bacteria responsible for urinary infection after urological or gynaecological procedures sometimes came from the same patient, but more often came from other patients by cross-infection. The principal final route of entry was the urethra or the indwelling catheter lying in it. These findings led to the elaboration of methods of destroying bacteria in the urethra before operation, improving the disinfection of cystoscopes, and preventing the entry of bacteria via the indwelling catheter. Application of these methods reduced the incidence of infection after prostatectomy from 83% to 6%, and after emergency bladder drainage for acute retention of urine from 73% to 10%. A smaller improvement followed the introduction of closed bladder drainage after gynaecological operations.

Catheters, Indwelling↗