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Biomedical subjects

W A Gardner

Publications and source records attributed to W A Gardner.

At least 73 records · Page 4Linked to original sources

Crystalloids in prostatic hyperplasia.

Prostatic crystalloids previously reported only in association with carcinoma were identified in 3.6% of a series of 456 cases of prostatic hyperplasia. Seventy percent of cases with crystalloids contained multiple areas of typical hyperplasia. The incidence of crystalloids in cases of atypical hyperplasia was 9.6%. One patient subsequently developed adenocarcinoma of the prostate. The follow-up period of the majority of these patients is too short to allow evaluation of the prognostic significance of prostatic crystalloids with regard to the development of prostate carcinoma.

Adenocarcinoma↗

Immunocytochemical identification of trichomonads.

Trichomonas vaginalis is one of the more common pathogens of the genitourinary tract. Morphologic studies of trichomonal infections, however, have been hampered by the fragile nature of these thin-walled flagellates and the lack of specific histochemical procedures to identify the fragmented organisms found in tissue sections. These limitations have usually restricted positive identification to smears of freshly obtained specimens. In an attempt to overcome these limitations, a rabbit antiserum specific for Trichomonas organisms was produced by repeated subcutaneous injections of a documented strain of T vaginalis maintained in vitro. Using this antiserum, immunoperoxidase techniques have been modified so that trichomonads have been clearly identified both in smears and in paraffin-embedded tissue sections. This method seems to be useful in establishing the presence of these organisms in tissue and may subsequently contribute to the histopathologic definition of trichomoniasis in man.

Animals↗

Blood transfusion practices in surgery: an approach to intrahospital analysis.

This study presents a two-year experience with the use of methods for the intrahospital analysis of surgical blood transfusion practices. Statistical and graphic methods were used to classify 21 types of operations (comprising 2,261 surgical procedures) by patterns of blood requests and usage. Surgical procedures were separated into three groups based on the frequency of transfusion. The results show that for many procedures careful attention to preoperative diagnoses can be very useful in predicting the amount of blood needed for a given surgical procedure. Methods described in this paper could be very helpful in reducing excess labor and preventing the unnecessary blood wastage which can result from improper ordering of blood for surgical procedures.

Blood Transfusion↗

Adenocarcinoma arising in a sigmoid diverticulum: report of a case.

A case of adenocarcinoma arising in a sigmoid diverticulum is presented. A patient who had colonic diverticulosis was found to have one diverticular lumen distended by tumor mass. Microscopically, this was seen to be adenocarcinoma arising from the diverticular mucosa. Apparently, this is the first reported case of adenocarcinoma arising in an intact diverticulum of the colon.

Adenocarcinoma↗

Primary small bowel plasmacytoma with intracellular fibrils.

This is a report of a rare plasma cell tumor, an extramedullary plasmacytoma arising in the small bowel. The tumor first occurred in the jejunum without evidence of multiple myeloma. One year later, classical signs of multiple myeloma appeared. The rarity and unusual course of this tumor plus the finding of intracellular fibrils make the case worthy of note.

Humans↗