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Biomedical subjects

W A Jackson

Publications and source records attributed to W A Jackson.

At least 19 recordsLinked to original sources

Some notes on an early nineteenth century manuscript medical receipt book.

There are 97 remedies listed, including 11 veterinary ones. These numbers include several that are duplicates. The commonest types of medicament are salves or ointments, of which there are ten, but these ten do not include ointments for specific complaints such as haemorrhoids or scurvy. The most frequently found cures are for the itch (10), rheumatism (5), gravel (4), pain (4), and piles (3), all the others having only one or two entries. They were intended to treat 39 human complaints and 9 animal ones. In addition there were formulae for killing lice, making rat poison, and preparing damson wine! The number of different medicaments that were used in the recipes was relatively small, but more than were to be found in the smaller sizes of domestic medicine cabinet. In 1820 Reece's Traveller's Dispensary that was flat and would fit in the pocket of a carriage, only contained ten drugs plus court plaster, lint, scales and weights with a book of directions and cost L3.10s.0d. (L3.50). The Lady's Dispensary which contained twenty medicines, including two pills, with some dispensing equipment and a book of directions cost L5.10s.0d. (L5.50). In all, he listed twenty different cabinets and a sea medicine chest ranging in price from L3.10s.0d. to L32.10s.0d. They included ones suitable for the family, country clergymen, and travellers on the continent and in the tropics. In 1862 Savory and Moore stocked a range of sixty-seven different medicine chests and cases in rosewood, mahogany, walnut, boxwood and leather that were fitted with 'modern appliances and conveniences adapted for the requirements of families, clergymen, officers, owners of yachts, and travellers.' Unfortunately no prices are quoted. I think that we can safely assume that the treatment received at the hands of Evan Jones was likely to be rather rough and ready when compared to the ministrations of a physician, surgeon, clergyman or local 'Lady Bountiful', but, nevertheless, must have been of great value to those who could not afford professional treatment.

Dispensatories as Topic↗

Frame food diet.

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Advertising↗

Translation of Ser16 and Thr17 phosphorylation of phospholamban into Ca 2+-pump stimulation.

Stimulation of cardiac sarcoplasmic reticulum Ca 2+-pump activity is achieved by phosphorylation of the oligomeric protein phospholamban at either Ser16 or Thr17. The altered mobility of phosphorylated forms of pentameric phospholamban has been utilized to demonstrate that the mechanisms of phosphorylation of the two sites differ. Phosphorylation of Ser16 by the AMP-dependent protein kinase proceeds via a random mechanism [Li, Wang and Colyer (1990) Biochemistry 29, 4535-4540], whereas phosphorylation of Thr17 by calmodulin-dependent protein kinase is shown here to proceed via a co-operative mechanism. This co-operative reaction mechanism was unaffected by the phosphorylation status of Ser16. These two mechanisms of phosphorylation generate very different phosphoprotein profiles depending on whether the Ser16 or Thr17 residue is phosphorylated. The translation of these patterns of phosphorylation into Ca 2+-pump function was reviewed using a fluorimetric Ca 2+-indicator dye, fluo-3, to measure Ca2+ uptake by cardiac sarcoplasmic reticulum vesicles. The rate of Ca2+ accumulation, which parallels Ca 2+-pump activity, was stimulated in proportion with the stoichiometry of phospholamban phosphorylation, irrespective of whether phosphorylation was on Ser16 or Thr17.

Aniline Compounds↗

Population growth: a comparison of evolutionary views.

"Economists are divided about population growth: the pessimism of neo-Malthusians contrasts strongly with the optimism of cornucopians. Despite their differences, however, both schools of thought reject economic orthodoxy and prefer evolutionary forms of theory. Their interpretations of evolution are different: the neo-Malthusians appeal to the entropy law, whereas the cornucopians emphasize human creativity expressed through markets. [The author argues] that both schools are right to adopt an evolutionary outlook, but that they are too restrictive in their conception of evolution. A more complete evolutionary view, which allows properly for social institutions, could give a more balanced account of population growth."

Demography↗

Population ageing and intergenerational conflict: a post-Keynesian view.

The author reexamines the relationships among demographic aging, the dependency burden, and intergenerational conflict from a post-Keynesian perspective, in which unemployment and excess capacity are normal to the functioning of capitalist economies, and resources are not generally fully utilized. He "argues that the Keynesian process of national income determination precludes any immediate relationship between population ageing and the 'burden' imposed on income recipients. Below full employment, a rising dependency ratio is not guaranteed to reduce the expenditure share of income recipients or raise their tax rates. An exclusive emphasis on intergenerational conflict can give a misleading impression of the consequences of population ageing." The focus is on developed countries.

Demography↗

Utilitarian pension and retirement policies under population ageing.

The author analyzes population aging and its impact on pension and retirement policies by utilizing a simple utilitarian model for alternative types of pension finance. Findings indicate that "when specific adjustments to population ageing are necessary, changes in the retirement age are preferred to changes in pensions or contributions." A geographical focus on developed countries is implied.

Age Factors↗

Baunscheidtism.

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Complementary Therapies↗

Pneumocephalus associated with a frontoethmoidal osteoma.

A 51-year-old man complained of a headache of 2-months duration. Computerized tomography revealed pneumocephalus and an osteoma at the confluence of the frontal and ethmoid sinuses on the right. Craniotomy confirmed an osteoma with a spur as the cause of the pneumocephalus.

Bone Neoplasms↗

Brockedon's press.

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History, Modern 1601-↗