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Biomedical subjects

W A Oliver

Publications and source records attributed to W A Oliver.

14 recordsLinked to original sources

Pleurectomy for persistent pain in benign asbestos-related pleural disease.

BACKGROUND: Persistent severe pain is a rare complication of benign asbestos-related pleural disease. METHODS: Four patients are described in whom pain persisted for more than one year (range 18 months to five years) which was incompletely relieved by opioid medication and nerve blocking procedures. All underwent pleurectomy in an attempt to relieve it. RESULTS: At operation the pleura was considerably thickened in all cases. Two of the four patients had successful relief of pain. The other two had a neuralgic component to their pain before surgery which persisted afterwards. One of these patients underwent successful cervical cordotomy. CONCLUSIONS: Pleurectomy may provide relief in patients with constant pleuritic pain due to benign asbestos-related pleural thickening. It seems, however, that patients in whom the pain has a neuralgic component are unlikely to benefit.

Adult↗

Endobronchial nocardial infection.

The rare presentation of nocardial infection as an endobronchial "tumour" is reported. Haematogenous dissemination occurred after fibreoptic bronchoscopy and biopsy, a phenomenon not previously described in nocardial infections. This case highlights the difficulties in diagnosing pulmonary nocardial infection and the potential for invasive procedures to disseminate the disease.

Aged↗

Diaphragmatic paralysis following cervical herpes zoster.

A 74-year-old man was found to have a paralysed left hemidiaphragm within four months of the appearance of a typical herpes zoster rash involving his left shoulder and neck. Investigations, including bronchoscopy and computed tomography of the chest, failed to detect a cause for the diaphragmatic paralysis. We believe that the cervical zoster and diaphragmatic paralysis were causally related, a rare but recognised association.

Aged↗

Pleuropulmonary fibrosis due to bromocriptine treatment for Parkinson's disease.

Pleuroplumonary fibrosis is an uncommon but potentially serious adverse effect of bromocriptine used in the treatment of Parkinson's disease. Two cases of this reaction, which occurred 12 months and 5 months respectively after commencing therapy are here reported. In both instances prompt clinical and radiological improvement occurred when bromocriptine intake was ceased. Fibrotic reactions to bromocriptine may be mediated by a serotonergic mechanism. Periodic monitoring of pulmonary symptoms is warranted in patients receiving bromocriptine treatment for Parkinson's disease.

Aged↗

Hydrocortisone-induced anaphylaxis.

Two patients with asthma developed an anaphylactic reaction after the intravenous administration of hydrocortisone. In both cases, the reaction included the rapid development of airflow obstruction. Previous reports have suggested that the allergenic component may be hydrocortisone itself, rather than the diluents or preservatives. When administering hydrocortisone, one should be aware of the possibility of such a reaction, even though it is uncommon. Although potentially life-threatening, particularly in an asthma sufferer, this reaction should be reversible with prompt recognition and appropriate management.

Aged↗

Scrotal implantation of the inflatable penile prosthesis.

Erectile impotence has been a problem for the patient and a frustration for the physician since the beginning of medical history. The inflatable penile prosthesis rapidly is becoming the standard for treatment of organic erectile impotence. A technique is described for implantation through a single midline scrotal incision. Intra-abdominal reservoir placement is possible through this incision. The technique shortens operative time and hospital stay, and minimizes postoperative patient discomfort. Of the 31 patients who have been managed in this way the postoperative course for 18 is more than 12 months. The results as judged by patient and sexual partner have been excellent to date.

Erectile Dysfunction↗

Myxoma of the mitral valve.

A case of myxoma of the mitral valve is reported. The clinical features were indistinguishable from left atrial myxoma with prolapse through the mitral valve. Because of the known tendency for these tumours to recur it was treated by wide excision which necessitated replacement of the mitral valve.

Adult↗

Surgical management in atypical pulmonary tuberculosis (MAIS complex).

Forty-four patients with Mycobacterium avium-intracellulare-scrofulaceum (MAIS) complex pulmonary infection who had a surgical procedure for management of their disease are reviewed. Relapse occurred in three cases and two patients died as a late result of their surgery. This gave a satisfactory treatment result in 89% of cases. The follow-up period was from nine months to 14 years after surgery. It is suggested that, despite the advent of modern antituberculosis drugs, resection of lung tissue is still the treatment of choic in suitable cases.

Adult↗

Tuberculosis in renal transplant patients.

Infection of two renal transplant recipients with tuberculosis is reported. Autopsy findings are available in one case. The frequency of tuberculosis in such cases, treatment problems and prevention are discussed.

Adult↗