PubMed Health⌕ Search

Biomedical subjects

W A Valder

Publications and source records attributed to W A Valder.

12 recordsLinked to original sources

[Cardiotoxicity of fenoterol - ultramorphologic and morphometric studies of the rabbit myocardium].

Beta-sympathomimetic drugs in large doses can induce necrosis of the myocardium, according to animal-experimental studies mainly with isoproterenol. In the instance of its broad clinical application in tocolysis a possible cardiotoxic effect of fenoterol has also been discussed. It was interesting to study the ultramorphologic effects of fenoterol on rabbit myocardium after a ten-day-application period. These tests revealed no myocardial-toxic alterations after monotherapy or in combination with verapamil or prednisolone (applying therapy-equivalent doses); a morphometric-statistical analysis confirmed these findings.

Abnormalities, Drug-Induced↗