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Biomedical subjects

W A Welton

Publications and source records attributed to W A Welton.

15 recordsLinked to original sources
PubMed1990

Mohs micrographic surgery.

Mohs micrographic surgery has been highly successful in treating skin cancers that grow in a contiguous manner. The technique requires removal of involved tissue in thin layers and histographic mapping to pinpoint residual tumor. This process is repeated until all of the tumor is resected. This allows 100 percent of all margins to be examined and is very tissue conservative, attributing to its unsurpassed cure rates and excellent cosmetic results. Since it is done as an outpatient procedure under local anesthetic, it also is safe and efficient.

Basal Cell Carcinoma↗
PubMed1986

Continuous ambulatory peritoneal dialysis for psoriasis. A report of four cases.

Four patients with psoriasis were treated with continuous ambulatory peritoneal dialysis (CAPD). Two were being treated for renal failure; the other two had normal renal function and were being treated exclusively for psoriasis. With CAPD at a rate of three to four exchanges per day, the psoriasis cleared completely in the two patients with renal failure and improved in the other two. In the patients without renal failure, low-flow peritoneal dialysis (one exchange per day) seemed to be of some value in maintaining remission but was ineffective in treating more active disease. Long-term therapy (greater than or equal to 12 weeks) with three or four daily exchanges may be needed for initial complete remission, and continuous treatment may be needed to prevent relapse. Thus, CAPD shows promise for the study of psoriasis and may be a last-resort treatment for severe, disabling cases.

Adult↗
PubMed1985

Pseudouremic pruritus: a scabies epidemic in a dialysis unit.

A scabies epidemic was studied in a university hospital dialysis unit. Itching in patients was initially attributed to uremic pruritus, and diagnosis of the epidemic was delayed until cases occurred among the staff. Sixteen cases (seven patients and nine staff) were identified by survey questionnaire and dermatologic examination. Application of 1% lindane lotion (Kwell, Reed and Carnrick, Piscataway, NJ) to all patients dialyzed in the unit and the entire staff eradicated the epidemic. A dialysis unit-associated nosocomial scabies epidemic has not been reported before and may mimic uremic pruritus in dialysis patients.

Antiparasitic Agents↗
PubMed1984

Scanning electron microscopic evaluation of tinea versicolor. Effects of treatment with miconazole nitrate and clotrimazole.

A study of tinea versicolor organisms was conducted in one patient by scanning electron microscopy. Morphologic changes in the organisms during treatment with topical clotrimazole and miconazole nitrate consisted of initial wrinkling of the surface, followed by fragmentation. These changes may have reflected cell wall alterations resulting from inhibited ergosterol synthesis induced by both treatment agents. The two drugs were effective in eliminating the organisms.

Administration, Topical↗
PubMed1978

Lymphangioma circumscriptum. A case with deep lymphatic involvement.

Lymphangioma circumscriptum is a rare disorder that is localized to the skin. To our knowledge, involvement of deeper lymphatic structures has been reported on only two prior occasions. Our patient had typical lymphangioma circumscriptum of her inner thigh, which was associated with deep lymphatic involvement and enlargement of the extremity. We report this case to alert others to this disease entity.

Adolescent↗
PubMed1977

Sign of Leser-Trélat.

We report a case of squamous cell carcinoma of the lung associated with the sudden appearance of seborrheic keratosis and acquired ichthyosis. We conclude that the sign of Leser-Trélat is a rare cutaneous manifestation of internal malignant disease.

Age Factors↗