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Biomedical subjects

W Adolph

Publications and source records attributed to W Adolph.

At least 19 recordsLinked to original sources

[Sonography of the thyroid].

The thyroid gland provides ideal anatomic conditions for sonographic investigations. Apart from the scintigraphy the sonography of the thyroid gland, therefore, stands in the first place as imaging procedure. After a short description of the investigation method and its ability of statement typical sonographic findings are demonstrated. The differentiation into diffuse or nodous strumata, the proof of typical focal findings such as autonomous adenomas or tumours or an increased vascularization in the region of the thyroid gland present an essential enlargement of the spectre of the modern diagnostics of the thyroid gland.

Diagnosis, Differential

[Changes of the gallbladder wall in the sonogram].

In the diagnostics of the changes of the gallbladder wall the sonography occupies a leading role. In acute cholecystitis on the basis of the criteria mentioned the making of a diagnosis is possible. Polypoid or plane-like infiltrating changes of the wall of the gallbladder are ambiguous and with the exception of the cholesterol polyps they are sonographically not always to be differentiated with sufficient certainty as benign (adenomas) or malignant (carcinomas) formations. When there is the least doubt about the dignity of the lesion of the gallbladder wall the continuing diagnostics (ERCP, CT) or the cholecystectomy is to be demanded.

Cholecystitis

[Tracheobronchomegaly--a case report].

On the basis of a casuistics is referred to the infrequent tracheobronchomegaly with disturbed respiratory mechanics (tracheal collapse) and relapsing bronchitides due to a congenital or acquired loss of elasticity of trachea and main bronchi. Bronchoscopy and bronchography ascertain the diagnosis which may be supposed already on the full-size X-ray by the demonstration of an abnormally wide trachea. The conservative therapy of the in most cases mucopurulent bronchitis for the purpose of the prevention of a global respiratory insufficiency apart from mucolytics often demands the application of antibiotics. In individual cases the prognosis may be improved by stabilizing operative corrections of the trachea and the resection treatment of accompanying bronchiectases.

Bronchitis

[Ultrasonic diagnosis in aneurysm of the abdominal aorta].

The sonographic diagnostics of an aneurysm of the abdominal aorta has obtained a high value on account of the high reliability and the rapid availability of the investigation in connection with the absolute safety of the method. Form, extension, calcification, haemodynamics, thrombosis and dissection of an aneurysm of the aorta can sonographically be demonstrated and measured by longitudinal and transversal sections. As non-invasive approach the ultrasound tomography in the order of the graduated diagnostic method stands before the computed tomography which is not always at once available and before the angiography which have their qualification in the case of a planned operative approach above all for the purpose of the exact topographic differentiation between suprarenal and infrarenal extension.

Aorta, Abdominal

[Ultrasound study of the spleen].

The sonography is the method of choice for the determination of the size of the spleen. Normally, this has, represented from the left flank, a size of 12 x 5 cm (length and thickness) and a regular structural pattern. Splenomegalies with diffusely changed echo-structure are found in infections, congestion spleens as well as haemoblastoses. Focal lesions are typical for cysts, abscesses and haematomas of the spleen. The sonography of the spleen plays a particular role in the staging of malignant lymphomas, whereas metastatic changes of the spleen may more infrequently be stated sonographically. The authors deal with the great importance of the sonography of the spleen in abdominal traumas.

Humans

[Percutaneous transhepatic bile duct drainage (PTCD)].

At the instance of a female patient with obstructive jaundice due to inoperable carcinoma of the head of the pancreas is reported on the percutaneous transhepatic cholangiodrainage. With the help of this non-operative palliative drainage of the system of bile ducts in malignant tumors of the biliopancreatic area an at least transitory relief with regression of the jaundice and the excruciating pruritus is achieved. With regard to the relatively high complication rate of the percutaneous drainages performed without laparotomy (haemorrhage, cholangitis, sepsis) and to the possibly already early loss of function by occlusion or dislocation of the catheter the indication for such an approach is strictly to be made.

Aged

[Lactacidosis in guanide treatment--a current disease syndrome].

It is reported on two eldery female diabetics with severe lethal lactacidosis. The clinical picture as well as the laboratory constellation leave no room for doubt about it, though only in one case the estimation of lactate could be performed. A renal insufficiency as involving factor is to be supposed in the two cases. With the help of literature the essential points of view of the clinical picture are discussed and it is referred to its origin also under influence of buformin.

Acidosis

[The course of asymptomatic diabetes under varying preventive therapy--concluding report of a 5-year prospective study].

During a prospective study the course of asymptomatic diabetes in different preventive treatment (diet, additionally tolbutamide, carbutamide or buformin) was observed concerning the frequency of manifestation and the behaviour of the oral glucose tolerance. Among the 100 protodiabetics after 5 years 38 clinical manifestations could be established, which finally nearly equally were distributed to all 4 groups of treatment. Only under the influence of buformin an effect preventing manifestation limited to 2 years appeared. Patients with persisting full or partial remissions continuously and more decreased in weight than cases of manifestation. Furthermore, the course was determined by the initially existing degree of hyperglycaemia as well as by the improvement of the glucose tolerance achieved in the first year. On account of the results of the examinations and the existing literature a preventive use of oral antidiabetics cannot be recommended.

Buformin

[Casuistic contribution to the clinical picture of idiopathic hypertrophic osteoarthropathy].

On the basis of a casuistic contribution is referred to the rare, hitherto not clarified clinical picture of the idiopathic hypertrophic osteoarthropathy (pachydermo-periostosis, Touraine-Solente-Golé syndrome). In pronounced cases the diagnosis can easily be made, when pachydermia, drumstick-fingers with watch-glass nails and hyperostotic changes of the skeleton are present. Differential-diagnostic difficulties concerning the osteoarthropathie hypertrophiante pneumonique (P. Marie-Bamberger) are the result as in the present case in abortive forms of the syndrome.

Adult

[Comparative analysis of electrocardiographic findings in diabetics and metabolically healthy persons].

The electrocardiograms of 447 diabetics and of the same number of non-diabetic test persons who were coordinated as biostatic twins, taking into consideration age, sex, and weight, were evaluated according to the Minnesota-code and compared. The cardiac endangering of the diabetics was most clearly expressed in the larger frequency of infarctions and the chronic-ischaemic heart disease which can be proved in all age groups. Diabetic males with short duration of diabetes showed the highest frequency of infarctions. The frequency of coronaropathy which is not increased in most age groups in the long-term diabetics compared with the control persons characterizes them as a positive selection of diabetics with an apparantly primarily low atherogenic potency. Hypertonus and/or adiposity were concomitant with a nearly doubled frequency of the ischaemic heart disease. The breadth of the P-wave as a possible reference to angiopathic changes in the region of the atrium was significantly larger in the diabetics in all age groups than in the control group.

Adult

[Long-term diabetes--a special form of diabetes].

Two hundred and eight long-term diabetics from the diabetic population of one district were examined thoroughly by physicians of the several special branches and compared with a control group consisting of biostatic twins with a healthy metabolism. Case control was performed for 5 years. The frequent absence of pathological findings in the coronary, peripheric and cerebral regions as well as a significantly high percentage of standard weight and underweight were found to be characteristic signs in that patients who survived their diabetes for several tens of years. Five years after the first registration, 68 long-term diabetics and 23 subjects of the control group had been died. However, the excess mortality does not surpass the mortality of subjects diseased for a short period. Besides the age and the duration of the manifestation, the survival rate was found to be dependent on the degree of the micro- and macroangiopathies, hypertension and over-weight. On the other hand, the duration of the diabetes and the metabolic condition did not exert any perceptible influence.

Age Factors

[Electrocardiographic findings in a selection-free number of cases of long-term diabetic patients].

When the conventional ECG after resting was used for establishing frequency and degree of severity of the ischaemic heart disease the stronger cardiac endangering of the longterm diabetic could be ascertained only from residues of an infarction (pathologic Q- and QS-types). With regard to all electrocardiographic criteria of the ischaemic heart disease according to the WHO-definition concerning the coronary risk a dependence on age, over-weight and increase of blood pressure was found without essential differences between the two groups. According to data in literature ischaemic reactions in diabetics are significantly more frequently to be expected only by inclusion of the electrocardiogram after work. Among the group of diabetics the frequency of the ischaemic heart disease increased with the duration of the disease. In contrast to retinopathy there was no dependence on the quality of the metabolic condition.

Adult