Conjunctival granulomas in rosacea.
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Aged↗
Biomedical subjects
W B Jackson
Publications and source records attributed to W B Jackson.
Cataract extraction in uveitis: comparison of aphakia and posterior chamber lens implantation.
We reviewed the charts of 39 patients (45 eyes) with uveitis who underwent cataract extraction (intracapsular or extracapsular) with or without implantation of a posterior chamber intraocular lens (IOL) at the Royal Victoria Hospital, Montreal, between 1981 and 1990. The nine eyes with Fuchs' iridocyclitis in which an IOL was implanted had good visual results and few postoperative complications. The 18 eyes with uveitis other than Fuchs' iridocyclitis that received an IOL did not show a greater risk of postoperative complications than those left aphakic (n = 17), and the postoperative visual acuity was comparable to that of the aphakic eyes. Although the numbers are small, we conclude that the presence of uveitis does not automatically exclude posterior chamber pseudophakia.
Adult↗
Idiopathic conjunctival granulomas.
A 12-year-old white boy presented with a 1-year history of intermittent bilateral follicular conjunctivitis with yellowish bulbar and limbal nodules and few symptoms. Histopathological examination of conjunctival biopsy specimens showed non-caseating epithelioid cell granulomas with giant cell formation. The lesions partially responded to therapy with topical corticosteroids but persisted for another 4 years and then gradually cleared over the next 5 years. A systemic investigation failed to disclose a specific cause. At the time of writing, the nodules had completely resolved and no associated systemic disease had developed.
Child↗
Schnyder's crystalline corneal dystrophy in association with hyperlipoproteinemia: histopathological and ultrastructural findings.
A 61-year-old man with Schnyder's crystalline corneal dystrophy showed a slight reduction in vision during 16 years of observation. Plasma lipoprotein analysis done 10 years after presentation showed type IIA hyperlipoproteinemia, which was also detected in one of four siblings examined, none of whom showed the characteristic corneal dystrophy. Electron microscopic studies on corneal biopsy specimens from the patient showed abundant crystalline material and vacuoles predominantly in the superficial corneal stroma, with occasional keratocytes and rare basal epithelial cells containing laminated structures. The findings of a focal continuity between the trilaminar membrane around some of the stromal vacuoles and the plasmalemma of the keratocytes as well as dissolution of the plasmalemma in other keratocytes are consistent with the hypothesis of a local cellular role in the development of this corneal disorder.
Cornea↗
A congenital ichthyosiform syndrome with deafness and keratitis.
This is a report on two children with a syndrome characterized by an extensive congenital ichthyosiform eruption, neurosensory deafness, hypotrichosis, partial anhidrosis, and vascularization of the cornea. The facial involvement is distinctive. Other features are dystrophy of the nails and tight heel cords. Both children are of normal intelligence. The inheritance pattern is unknown.
Child↗
The effect of oxisuran, a selective inhibitor of cellular immunity, on the rejection of bovine corneal xenografts in rabbits.
Oxisuran, a selective inhibitor of cellular immunity, delayed the rejection of bovine corneal xenografts when it was administered intraperitoneally to rabbits. The drug produced no significnat effect on the production of humoral antibody in response to injected sheep erythrocytes.
Animals↗
The TRH test: its value in the diagnosis of Graves' ophthalmopathy.
When a goiter or hyperthyroidism is absent, the diagnosis of ophthalmic Graves' disease is often difficult. We evaluated the thyrotropin (TSH) response to intravenously administered thyrotropin-releasing hormone (TRH) in fourteen patients presenting with proptosis or lid retraction. All of them had normal results with routine thyroid function tests and in most a T3 suppression test and orbital ultrasonography were performed. We found an absent or impaired response to TRH in the patients with Graves' ophthalmopathy which correlates well with their having a non-suppressible thyroid gland. Patients with orbital tumours, pseudotumours or congenital lid retraction responded normally to TRH. The TRH test was easier and as reliable as the T3 suppression test in the investigation of a patient with suspected Graves' disease.
Adolescent↗
Talc retinopathy.
We observed talc particles in the retinal vessels of nine out of 17 addicts to intravenous methadone. The retinopathy was found in patients who had injected more than 9,000 tablets. In seven the chest roentgenograms showed a diffuse micronodular pattern which progresses to resemble massive pulmonary fibrosis and is associated with severe disability. The ophthalmologist must recognize this entity since he may be the first to identify drug abusers who inject oral medications containing talc. Early detection and counselling may prevent the severe pulmonary complications.
Adult↗
Adenovirus type 19 keratoconjunctivitis in Canada.
We describe an outbreak of epidemic keratoconjunctivitis occurring in Montreal during the winter of 1974. Adenovirus type 19 was the only virus isolated. We confirm the presence of type 19 adenovirus in Canada; it produces severe keratoconjunctivitis. The incubation period, method of spread and clinical findings resemble those seen in outbreaks of type 8 EKC. The prevalence of adenovirus type 19 in the population of Canada is unknown. Although some object to the use of the term EKC for infection caused by adenoviruses other than type 8, we believe that EKC should be regarded as an entity requiring virus isolation and antibody determination to identify the adenovirus type responsible for it.
Adenoviridae↗