PubMed Health⌕ Search

Biomedical subjects

W B Kingsley

Publications and source records attributed to W B Kingsley.

At least 19 recordsLinked to original sources
PubMed1991

Glandular excision in total glandular mastectomy and modified radical mastectomy: a comparison.

Total glandular mastectomy and modified radical mastectomy were compared for the amount of breast tissue remaining after surgery. Multiple biopsies were taken from the anterior chest walls of women following total glandular mastectomy (N = 27) and modified radical mastectomy (N = 28) to try to detect any residual glandular tissue. Regardless of procedure performed, breast tissue was identified histologically in 5 percent of all biopsy specimens (159 and 161, respectively). One of every five operative fields was shown to have glandular elements in at least one of the biopsy sites; the positive biopsies did not form a discernible pattern. The residual breast tissue in each of these patients averaged less than 1 gm. On the basis of this study, modified radical mastectomy and total glandular mastectomy appear to be equally effective in removing most of the breast.

Biopsy↗
PubMed1985

What constitutes adequate study of axillary lymph nodes in breast cancer?

This study was undertaken to determine the value of the clearing technique and multilevel sectioning of lymph nodes to aid in optimally examining axillary dissections for lymph node metastases. One hundred consecutive mastectomy specimens with axillary dissections were initially examined by our routine technique: examination of fat for lymph nodes by inspection and palpation and examination of one microsection from each lymph node. The remaining axillary tissue was then cleared using the technique of Durkin and Haagensen and each of the originally examined lymph nodes was resectioned at two additional deeper levels. In our routine examination, 2203 lymph nodes were found with 211 lymph nodes containing metastatic tumor. Clearing disclosed 412 additional lymph nodes, of which 17 contained metastatic tumor. The two additional microsections of lymph nodes revealed tumor in only two lymph nodes which were initially free of tumor. The extended study of the axilla did not add significantly to our routine examination.

Axilla↗
PubMed1980

Nonamyloid green birefringence following Congo red staining.

It was noted recently in our laboratory that the Congo red-stained sections of a muscle and sural nerve biopsy specimen showed the typical green birefringence associated with amyloid, but no amyloid could be demonstrated with electron microscopy. A study involving three different dyes, two different procedures, and six different fixatives revealed that the technique utilized was the most important consideration. With the exception of Carnoy's mixture, the fixative was relatively unimportant and the false birefringence was closely related to excess dye retained in the tissue.

Amyloid↗