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Biomedical subjects

W B Stephens

Publications and source records attributed to W B Stephens.

15 recordsLinked to original sources

Changes in blood pressure and antihypertensive treatment in a community over four years.

In 1971 persons aged 50 to 59 years in Albury were screened for hypertension and those with diastolic blood pressure equal to or over 110 mm Hg were notified. On screening of the sample in 1975, the proportion of persons receiving treatment had doubled to 22%. Most of those newly receiving treatment in 1975 had had diastolic blood pressures under 110 mm Hg in 1971. The mean systolic and diastolic pressures of the newly treated group had fallen by 13-7 and 9-1 mm Hg respectively to 153-5 and 91-6 mm Hg. The mean pressures of subjects already receiving treatment in 1971 and continuing it remained higher (163-1 mm Hg systolic and 100-9 mm Hg diastolic), despite their receiving relatively more medication. The latter group was composed of patients likely to have had more severe hypertension originally, and the importance of effective treatment for them is emphasized. The frequency with which subjects with mild hypertension are being treated demonstrates the urgent need to complete randomized controlled trials of treatment in this group.

Adrenergic beta-Antagonists↗

The rate of initiation of treatment for hypertension in a community, 1971--1975.

In 1971 persons aged 50-59 in a community were screened for hypertension and those with diastolic BP greater than or equal to 110 mmHg were notified. On reviewing the sample in 1975 the treatment rate had doubled to 22%. Screening in 1971 was followed by an immediate rise in numbers starting treatment, most being notified cases. Thereafter initiation of treatment at a rate of 3-8 cases per 100 persons per year chiefly reflected identification of subjects deemed to need treatment in the ordinary course of medical practice. Of those starting treatment during the four years 25% had stopped it by 1975. The influence of screening and other factors on the rate of initiation of treatment and adherence to it are discussed. With an already high attendance rate at doctors, regular screening of this whole age group seems feasible within the framework of general practice. The high treatment rate found in 1975 underlines the urgent need for the indications currently used for starting treatment to be validated.

Attitude of Health Personnel↗

Fascioliasis causing hepatitis in two eaters of water cress.

Fasciola hepatica infection of the liver in a husband and wife occurred after they had eaten water cress exposed to pollution by cattle. Diagnosis was a problem. Both responded to treatment with chloroquine and emetine. The epidemilology and pathology of infection of the liver by Fasciola hepatica are described. The danger of eating water cress is emphasized for this momentary delight may lead to a chronic debilitating illness.

Aged↗