Biomedical subjects
W B Weil
Publications and source records attributed to W B Weil.
Overtreatment of neonates.
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All children deserve to have their basic needs met.
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Fatal fungal peritonitis in an adolescent on continuous ambulatory peritoneal dialysis: association with deferoxamine.
An unusual case of Rhizopus microsporus (mucormycosis) fungal infection in a teenage boy on continuous ambulatory peritoneal dialysis is presented. Premortem cultures were negative and the patient developed a rapidly disseminated fatal infection. The patient was being treated with deferoxamine (DFO) for iron and aluminum overload. An argument is made for a probable association between DFO and this fatal fungal infection in patients with end-stage renal disease.
Ethical issues in pediatrics.
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Clinical decision-making in catastrophic situations: the relevance of age. Report of a conference convened by the American Geriatrics Society, April 17-18, 1987.
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Problems related to personal autonomy and informed consent.
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Review of 'Neglect of chronically ill children'.
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The Baby Doe regulations: another view of change.
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The aftermath of Baby Doe in the US.
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Issues associated with treatment and nontreatment decisions. Special reference to newborns with handicaps.
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Energy balance in low-birth-weight infants.
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The effect of polybrominated biphenyl on infants and young children.
The effects of PBB on 33 children born between September 1, 1973, and December 31, 1975, were evaluated in September, 1977. These children, born to families who lived on quarantined farms, were compared to 20 children who were not exposed to PBB. The birthdate interval was selected to obtain children who were exposed in utero or in early infancy or both, the two time periods when damage to developing tissues and organ systems should have been maximal. The results of these studies failed to identify any effects on physical growth, physical examination, or neurologic assessment, although the parents indicated by historical review that the exposed children had had more illnesses, especially respiratory, than had the control children. There were some indications of an inverse relationship between PBB fast level and performance on selected developmental tests.
National dietary goals. Are they justified at this time?
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Current controversies in childhood obesity.
The conclusions that one can state with assurance are remarkably few. Adiposity in children is best monitored clinically by the measurement of skin-fold thickness. The likelihood that obesity will progress from infancy to childhood to adult life is still questionable and may be more important in the individual child than as a significant cause of adult obesity. Behavioral and social factors pedominate in etiology, yet biologic factors, including genetic, are also involved. Behavioral and social factors are critical in the significance of obesity to the individual. Although there are definite disease hazards, they appear to be predominantly confined to the very obese. The best treatment appears to be prophylaxis, again heavily involving behavioral and social factors as well as the wide-spread distribution of sound nutritional information. When prophylaxis fails, the behavioral modification approach to therapy currently holds the greatest promise.
Letter: Mortality factors in diabetes.
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