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Biomedical subjects

W Böhland

Publications and source records attributed to W Böhland.

15 recordsLinked to original sources

[Nutritional status in stomach cancer--a criterion for evaluating operability?].

The nutritional status of 41 male patients with carcinoma of the stomach was recorded, right after admission to hospital, and was related to tumour-specific operability. The nutritional condition of most of the patients was moderately impaired. Significant differences between operable and non-operable patients were recorded from the following parameters: upper-arm circumference, haemoglobin concentration, serum albumin, pseudocholinesterase, intradermal testing, E-rosette count. The findings thus obtained provided some limited information on operability.

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[Immunotherapy of burns--animal experiments].

Immunologic changes are a component of the pathophysiology of severe burns. The effect of the burn toxin can be reduced by immunologic mechanism. The antigen elimination by immunologic defense mechanism additionally to the necrectomy was discussed. A significant therapeutic effect after standardised burn in the animal mouse model showed the application of heterologous antibodies against the burn antigen and the specific immunostimulation. The antibody titre and the number of lymphocytes which bind burn toxin were investigated. The animal experimental results show the real chances of the antigen elimination by passive immunisation respectively immunostimulation. Immunosuppressive influence by therapeutic measures must be avoided.

Animals↗

[Effect of infection on the immune system in burns in animal experiments].

After discussing a model of infection in mice and the possibility of active immunization against pyocyanic pseudomonas, the authors describe the effect of a lipid-protein-complex achieved from isolated burnt mouse skin on pseudomonas infection. First results showed that sublethal amounts of that complex at otherwise less pathogenic suspension of pseudomonas cause a lethality of 100 per cent. This effect can partially inhibited by application of antitoxic IgG. The lethal course was not primarily caused by the infection but by the above mentioned complex which significantly lowers the resistance against pyocyanic pseudomonas.

Animals↗