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Biomedical subjects

W Barina

Publications and source records attributed to W Barina.

7 recordsLinked to original sources

Pancreatic duct stenosis mimicking a tumor due to an aberrant vessel.

A case of a 74-year-old man is reported who had liver cirrhosis and a mass lesion in the left liver lobe. The search for a potential primary tumor showed a filiform duct stenosis in the pancreatic head on ERCP. The presumptive diagnosis of a pancreatic tumor with a liver metastasis was made. Due to the poor general condition of the patient no further diagnostic steps were undertaken and he died four weeks later from progressive liver failure. On autopsy an aberrant vessel originating from the superior mesenteric artery (arteria pancreatico-duodenalis dextra superior) was found to cause the ductal stenosis; an hepatocellular carcinoma in the left liver lobe, but no pancreatic tumor was detected.

Aged↗

Endoscopic injection of fibrin glue versus polidocanol in peptic ulcer hemorrhage: a pilot study.

In this prospective, randomized trial, bleeding gastroduodenal ulcers in the Forrest I and II stages were treated endoscopically with injection of either fibrin glue or polidocanol. After exclusion of four patients for various reasons, 38 patients were treated with fibrin glue (mean: 5.4 ml) and 41 patients with polidocanol (mean: 12.1 ml) with control endoscopies routinely performed on days 1, 3, and 7 after treatment. The two groups were comparable with regard to age, sex, ulcer location and Forrest classification. Recurrent bleeding was observed in five cases in the fibrin group and in ten cases in the polidocanol group; three and two patients in the fibrin and polidocanol groups, respectively, had to undergo surgery. We conclude that fibrin glue injection is an effective method for the treatment of bleeding gastroduodenal ulcers.

Adult↗

[Secondary aorto-duodenal fistulas as a cause of massive gastrointestinal hemorrhages].

Aorto-duodenal fistulas represent a rare but highly dangerous complication following reconstructive aortic interventions. They may be the source of severe gastrointestinal hemorrhages. The recognition of cause and localization of the latter may be difficult. Only an immediate diagnosis permits urgent surgical intervention and may prevent the otherwise fatal outcome. The importance of an early diagnosis is underlined by two case reports.

Aged↗

Human intestinal motor activity and transport: effects of a synthetic opiate.

Effects of opiates on intestinal motor activity and transport of water and electrolytes have been studied separately in previous investigations. The aim of these experiments was to evaluate simultaneously the effects of a synthetic opiate, loperamide, on motor activity and transport in the human intestine. Jejunal, ileal, and colonic perfusions were performed in 9 healthy volunteers. After application of loperamide (12 mg), cyclically recurring migrating motor complexes in the small intestine occurred at a significantly higher frequency than after application of placebo. This was primarily due to a decrease in the duration of irregular motor activity (phase II). Loperamide increased the transit time in the jejunum but not in the ileum or in the colon. Transport rates of water and electrolytes and transmural electrical potential differences were not significantly affected by the drug. These results suggest that opiates exert their constipating effect by inhibiting phase II-related irregular motor activity.

Adult↗