Biomedical subjects

W Barlow

Publications and source records attributed to W Barlow.

At least 37 records · Page 2Linked to original sources

PubMed1994

Effects of practice style in managing back pain.

OBJECTIVE: To assess the effects of a practice style of back pain management consistent with self-care (infrequent prescribing of pain medications and bed rest) on long-term functional outcomes, costs of care, and patient satisfaction. DESIGN: A quasi-experimental observational study in which primary care physicians (n = 44) were categorized according to one of three practice style groups defined by a low, moderate, or high frequency of prescribing pain medications and bed rest for many patients (average, 24 patients per physician). SETTING: Primary care practices of a large, staff model health maintenance organization, Group Health Cooperative of Puget Sound. PATIENTS: Consecutive patients with back or neck pain of participating primary care physicians. Patients were interviewed 1 month (n = 1071) and 1 year and 2 years (n = 911) after their index visits. RESULTS: Patients in the three practice style groups rated similarly the quality of medical care received for back pain. Patients treated by physicians who infrequently prescribed pain medications and bed rest were more satisfied with education about back pain. On a scale of 0 to 10, the mean rating of agreement with the statement, "After your visit the doctor, you fully understood how to take care of your back problem," was 5.6 +/- 3.6 among patients of physicians who frequently prescribed medication and rest and was 6.6 +/- 3.5) among those who infrequently prescribed medication and bed rest. At 1 month, 30% of patients of physicians who infrequently prescribed medications and bed rest were graded as having moderate to severe activity limitation because of back pain, whereas 37% of patients in the moderate group had this grading, and 46% of patients of physicians who frequently prescribed were graded as having moderate to severe activity limitation. Differences in activity limitation by practice style group were no longer evident at 1 or 2 years of follow-up. The total 1-year costs of back care were higher among patients seen by physicians who frequently prescribed bed rest and pain medications (cost, $768 +/- $1592) than among those seen by physicians who infrequently prescribed (cost, $428 +/- $665), due largely to differences in inpatient and specialty care costs. The adjusted difference in costs, after controlling for case-mix variables, was $277 (95% Cl, $85.50 to $471.32). CONCLUSIONS: A practice style consistent with back pain self-care yielded similar long-term pain and functional outcomes at lower cost and was associated with higher satisfaction with patient education compared with a practice style characterized by more frequent prescribing of pain medications and bed rest.

Adult↗

PubMed1993

Back pain in primary care. Outcomes at 1 year.

Outcomes of primary care back pain patients (N = 1128) were studied at 1 year after seeking care. Changes in depression depending on outcome, and predictors of poor outcome were evaluated. Less than one back pain patient in five reported recent onset (first onset within the previous 6 months). One year after seeking care, the large majority of both recent and nonrecent-onset patients reported having back pain in the previous month (69% vs. 82%). A significant minority of both recent and nonrecent-onset patients had either a poor functional outcome (14% vs. 21%) or continuing high intensity pain without appreciable disability (10% vs. 16%). Predictors of poor outcome included pain-related disability, days in pain, lower educational attainment, and female gender. Among initially dysfunctional patients with persistent pain, one half were improved and one third had a good outcome at the 1-year follow-up. Among initially dysfunctional patients who experienced a good outcome, elevated depressive symptoms improved to normal levels at follow-up. The outcome of back pain was predicted by pain-related disability and days in pain rather than by recency of onset, so it may be more meaningful to distinguish characteristic levels of pain intensity, pain-related disability, and pain persistence than to classify patients as acute or chronic.

Adult↗

PubMed1993

The impact of physician attitudes on patient satisfaction with care for low back pain.

We wished to determine whether patient satisfaction was related to physicians' confidence in their abilities to effectively manage low back pain, and to examine their attitudes about patients with back pain. The confidence and attitudes of primary care providers were determined using self-administered questionnaires. Patient satisfaction with care was assessed during telephone interviews conducted 3 weeks after a clinic visit for low back pain. The study was conducted in a primary care clinic of a large health maintenance organization. Completed surveys were obtained from 21 primary care providers (18 physicians and three physician assistants) and 270 of their patients with low back pain. Three satisfaction scales specific to low back pain were used to measure patient satisfaction with regard to information received from provider, caring, and effectiveness of treatment. The results showed that the providers' attitudes about patients with low back pain were not associated with any of the patient satisfaction measures. However, patients of more confident providers were significantly more satisfied with the information they received than were patients of less confident providers. These differences could not be explained by years in practice, length of visit, patient demographics, or the severity and duration of low back pain. These findings suggest that providers who have more confidence in their abilities to effectively manage low back pain may in fact be more effective patient educators.

Adolescent↗

PubMed1993

Patterns of antidepressant use in community practice.

Computerized pharmacy records from a large staff-model health maintenance organization were used to examine patterns of antidepressant use by primary care physicians and psychiatrists. Based on timing of prescription refills, patients treated by psychiatrists were more likely than those treated in primary care to continue medication for more than 30 days (35% vs 25%, p < 0.00001) and more likely to reach a prescribed daily dose of 100 mg of imipramine or the equivalent (48% vs 40%, p < 0.00001). Patients treated with newer antidepressants were significantly more likely to continue treatment past 30 days (range from 75% for fluoxetine to 54% for doxepin, p < 0.00001) and to reach an adequate daily dose (range from 51% for fluoxetine to 26% for doxepin, p < 0.00001). Psychiatrists more often prescribed newer antidepressants, and much of the difference between specialties could be explained by drug selection. These findings suggest more intensive antidepressant treatment than in earlier reports, especially in primary care. More intensive treatment with newer antidepressants may reflect more tolerable side effects, but these observational data are liable to selection bias. Any potential advantages of newer antidepressant medications must be balanced against significantly higher costs.

Adolescent↗

PubMed1992

Examination of the patient with a knee dislocation. The case for selective arteriography.

One hundred fifteen patients with a unilateral knee dislocation underwent arteriography to examine the popliteal artery. The incidence of popliteal artery injury was 23% (27 patients). Clinically, 29 (25%) of the 115 patients had an abnormal ipsilateral pedal pulse and 23 (79%) of these 29 patients had an arteriographically identified popliteal artery injury. Twenty-two arteries were surgically repaired and one was treated without surgery. Eight-six patients had normal pulses; the arteriogram showed no abnormalities in 77, demonstrated spasm in five, and revealed an intimal flap in four. All 86 patients were treated without surgery and had no delayed vascular complications. This demonstrates that the vascular examination is an accurate predictor of major popliteal artery injury following knee dislocation. Patients with an abnormal pedal pulse warrant arteriography due to a high incidence (79%) of popliteal artery injury. Patients with normal pulses may be monitored by clinical examination only. Popliteal artery injuries in this group are minor and rarely require intervention.

Adolescent↗

PubMed1992

The evolving surgical management of recurrent carotid stenosis.

The traditional approach to recurrent carotid stenosis has been repeat endarterectomy or patch angioplasty. Concern with the durability of repeat carotid endarterectomy has resulted in our use of carotid resection with autogenous graft interposition. This study was designed to determine the outcome and efficacy of carotid resection compared with repeat carotid endarterectomy in the management of recurrent carotid stenosis. From 1974 to 1991, 162 operations (repeat carotid endarterectomy 105, carotid resection 57) were performed for recurrent carotid stenosis. Indication for operation was hemispheric symptoms in 63% of patients, nonlateralizing symptoms in 25%, asymptomatic stenosis in 7%, and previous stroke in 5%. Ninety-one percent of patients had stenosis greater than 90% on arteriography. The perioperative stroke rate for carotid resection was 3.5%, with a subsequent rate of 0.0064 strokes per year. For repeat carotid endarterectomy, the perioperative stroke rate was 1.9% with a subsequent rate of 0.011 strokes per year. Graft patency after carotid resection was 93% (mean follow-up, 35 months). Four patients treated with carotid resection had graft thrombosis, and two of the four remained asymptomatic. After repeat carotid endarterectomy, one patient had carotid thrombosis, and recurrent stenosis greater than 50% developed in 23 patients (mean follow-up, 64 months). Twenty patients treated with repeat carotid endarterectomy underwent an additional operation for further symptomatic recurrent carotid stenosis. We conclude carotid resection is a safe and effective alternative to repeat carotid endarterectomy for patients undergoing operation for recurrent carotid stenosis.

Aged↗

PubMed1991

A comparison of methods for calculating a stratified kappa.

Investigators use the kappa coefficient to measure chance-corrected agreement among observers in the classification of subjects into nominal categories. The marginal probability of classification may depend, however, on one or more confounding variables. We consider assessment of interrater agreement with subjects grouped into strata on the basis of these confounders. We assume overall agreement across strata is constant and consider a stratified index of agreement, or 'stratified kappa', based on weighted summations of the individual kappas. We use three weighting schemes: (1) equal weighting; (2) weighting by the size of the table; and (3) weighting by the inverse of the variance. In a simulation study we compare these methods under differing probability structures and differing sample sizes for the tables. We find weighting by sample size moderately efficient under most conditions. We illustrate the techniques by assessing agreement between surgeons and graders of fundus photographs with respect to retinal characteristics, with stratification by initial severity of the disease.

Humans↗

PubMed1991

Methods, statistical features, and baseline results of a standardized, multicentered ophthalmologic surgical trial: the Silicone Study.

This article describes the trial design and baseline results for the Silicone Study, a multicenter, randomized surgical trial designed to compare the effectiveness of silicone fluid versus long-acting gas in the treatment of proliferative vitreoretinopathy (PVR). Design features include (1) standardization of the surgical protocol to reduce intersurgeon variability, (2) formulation of a PVR clinical classification system relevant to modern vitreoretinal surgery, and (3) creation of a photographic protocol to document PVR pathology. Statistical issues affecting the analysis of the outcome data include (1) the addition of a second group of patients with more severely diseased eyes after the trial began, (2) the change to a different long-acting gas during the course of the trial, and (3) recurrent retinal detachments that require reoperations with the randomized treatment, and, in some instances, a crossover from the randomized to the alternate treatment. Demographic and baseline ocular characteristics are presented for the two groups under study.

Adult↗

PubMed1990

Pars plana vitrectomy for acute retinal detachment in penetrating ocular injuries.

We studied 41 eyes with acute retinal detachment after penetrating ocular trauma in a retrospective cohort analysis. Pars plana vitrectomy was performed in 28 eyes, while the remaining 13 eyes had only primary repair and closure of the wound. The two groups differed in the type of trauma (more gunshot wounds in the vitrectomy group and more blunt injuries in the nonvitrectomized group). Visual success (visual acuity of 5/200 or better) was observed in 10 (37%) of the eyes treated by vitrectomy compared with one (8%) of the eyes in the nonvitrectomy group. Anatomic success was achieved in 21 (75%) of the eyes in the vitrectomy group but in only one (8%) of those in the nonvitrectomy group. Enucleation or phthisis was observed in seven (54%) of the eyes in the nonvitrectomy group compared with only five (18%) in the vitrectomy group. Significant prognostic factors for anatomic outcome in the vitrectomy group were the location of the laceration and the presence of the lens.

Acute Disease↗

PubMed1990

The effect of therapeutic treatment crossovers on the power of clinical trials. The Silicone Study Group.

The Silicone Study is a randomized clinical trial comparing two surgical methods for reattaching the retina when detachment is associated with proliferative vitreoretinopathy. If the retina redetaches subsequently, the patient will usually undergo additional surgery using the assigned treatment. In a limited number of cases the patient may be switched to the alternative treatment, if a "therapeutic crossover" is endorsed by an independent committee of ophthalmologists. A successful outcome is continued anatomic attachment of the retina and an adequate visual result 6 months after the final surgery. The therapeutic treatment crossovers affect the power of the trial to detect a difference between the two treatments. A simulation study shows that the loss in power depends on the magnitude and degree of bias in the probability of being switched from one treatment to the other. Unlike the usual case of lack of compliance, complete information about treatment history may allow statistical adjustment for the crossover. The outcome may be modeled using a multinomial distribution. Much of the power lost due to switching may be recouped under some strong assumptions.

Computer Simulation↗

PubMed1990

Ocular trauma in an urban population. Review of 1132 cases.

A retrospective survey was done of all ocular and adnexal trauma cases seen at a large metropolitan hospital during a 6-month period. By determining patient demographics, causes of the eye injuries, and extent of ocular damage, the authors hoped to delineate areas where preventive measures might decrease such trauma. Demographic and clinical data on 1132 patients were analyzed. Most patients were in the first three decades of life and were male. Blunt trauma was the most common type of injury. Assault was the most common cause and accounted for the highest number of serious injuries. Eye injuries associated with violence are difficult to prevent using conventional strategies that are usually effective in the home and workplace.

Adolescent↗

PubMed1989