PubMed Health⌕ Search

Biomedical subjects

W Berges

Publications and source records attributed to W Berges.

63 records · Page 4Linked to original sources
PubMed1979

Does dopamine predispose to gastroesophageal reflux?

In the American opossum dopamine causes a dose-dependant fall in the lower esophageal sphincter (LES) pressure. The effect in man is unknown. Therefore, the effect of two dosages of dopamine (1 mcg.kg-1 body weight.minute-1 and 5 mcg.kg-1 body weight.minute-1) was studied in ten healthy volunteers by pullthrough manometry. The results show that neither dopamine nor normal saline solution as a control changed LES pressure which is an important determinant of gastroesophageal sphincter competence. Thus, dopamine in clinically used doses does not appear to predispose to gastroesophageal reflux.

Adult↗
PubMed1978

[Cardiac arrhythmia during pneumatic dilatation of achalasia of the esophagus (author's transl)].

ECG was recorded in 38 patients with achalasia of the esophagus before, during and after pneumatic dilatation. During the dilatation both marked increases as well as decreases of heart frequency were observed. The mean values of all patients remained virtually unchanged. The most frequent type of arrhythmia were ventricular extrasystolies (16 patients), whereas supraventricular extrasystolies (4 patients), second degree-av-block (2 patients) and av-dissociation (1 patient) occured infrequently. In none of our patients arrhythmia was critical, even in a patient with preexisting cardiac insufficiency. Thus, patients with achalasia of the esophagus are not endangered to a major degree by cardiac arrhythmia during pneumatic dilatation.

Adult↗
PubMedDate not supplied

[Motility disorders of the gastrointestinal tract in old age].

Most motility disturbances of the gut in the agenarian are secondary in nature. So far, only in the oesophagus an alteration of the motility due to age has been demonstrated. Difficulties in methodology are a major reason for our lack in knowledge about the bowel movements in old age. Most studies have been done in the oesophagus and distal colon since these organs are easily accessible for intubation. The majority of the motility disorders in old age are due to problems which accumulate when man gets older, like diabetes mellitus, cerebrovascular disease and intake of numerous drugs. These conditions may directly or indirectly affect the motor organic diseases, particularly carcinoma, which may mimick functional disorders, by a careful diagnostic work-up. The therapy should try in the old as in the young to cure the underlying pathomechanism.

Aged↗