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Biomedical subjects

W Brühl

Publications and source records attributed to W Brühl.

At least 37 records · Page 2Linked to original sources
PubMed1975

[The effect of cholecystectomy on the lipid composition of the liver bile. Follow-up studies in 10 cholecystectomized patients with recurrent calculi in the bile ducts].

In 10 patients who had formed new stones in the common bile duct after cholecystectomy, the lipid composition of the hepatic bile was determined on three different days after relaparotomy and placing of T-tude and the cholesterol content of the stones was investigated. The cholesterol content in 9 out of 10 recurrent gallstones was between 78 and 93%. The lipid content was lithogenic in these 9 cases. In the tenth (a patient with mixed recurring gallstones) solubility for cholesterol was in the critical area. There thus seems to be no normalization of lipid composition in patients with cholesterol stones after cholescystectomy, and the conditions for recurrence of cholesterol stones remain unaltered.

Adult↗
PubMed1975

[Influence of efferent biliary ducts on the composition of bile acids. Studies on subjects with cholesterol gall stones and a stone-free control group].

Cadaveric livers and their gall bladders were used in order to determine the bile acids following separation by thin layer chromatography; spectrophotofluorimetry was employed. In the hepatic tissue of the lithiasis patients the bile acid concentrations and the ratio of the trihydroxycholanic acid (cholic acid) to the dihydroxycholanic acids (desoxycholic acid and chenodesoxycholic acid) are lower than in the control group. In the B-bile only cholic acid and the quotient cholic acid to chenodesoxycholic acid reveal any significant differences. Also, there exists an established positive correlation between the bile acid concentration in the hepatic tissue and in the B-bile of the alcoholic test persons but not in the cholelithiasis patients. From this we may infer that the concomitant inflammation of the gall bladder has an influence on the composition of the bile acids.

Autopsy↗