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Biomedical subjects

W C Beck

Publications and source records attributed to W C Beck.

At least 19 recordsLinked to original sources

Surgical glove powders bind latex antigens.

Latex surgical gloves have recently been identified as a potential source of allergens. Much of the current information suggests that the soluble proteins in latex may cause significant reactions in sensitive individuals. The starch powders used as a lubricant on some latex gloves have also been identified as potential allergens in some patients. In this study, we determined these powders to act as potential carriers of latex allergens. We have produced a polyclonal antiserum to be used as a reagent to study latex proteins. By Western blot analysis, we identified a significant interaction between latex proteins and starch powders. The binding of latex proteins to starch particles results in a glove particle that may have an increased potential to act as an allergen. The latex protein-starch particles represent a potential mechanism for exposure and sensitization of health care workers to latex allergens. Elimination of these particles from the operating room should reduce the route of sensitization and the potential for adverse reactions to latex.

Adsorption

Acute appendicitis. A 5-year review.

A startling 31 per cent rate of perforated appendicitis in 1984 prompted a 5-year review at the Guthrie Medical Center. An increase over previous rates of 13 per cent and 0 per cent in 1964 and 1944 was confirmed in this study. Perforation accompanied 44 of 240 cases of appendicitis (18.3%); diagnostic accuracy in 295 cases undergoing operation was 81.4 per cent. Groups at risk for perforation were patients in the first decade of life (34.3% with perforations) and those over 50 years of age (48% perforated). Perforation rates were generally inversely related to accuracy. Accuracy was poorest in women in the second to fourth decade or those in the mid-portion of the menstrual cycle. When the appendix was not perforated, complications occurred in 8.7 per cent of patients while 29.5 per cent with a perforation had a complication. The mean hospital stay was prolonged by 2.5 days if the appendix was perforated. An increased awareness of the risk by both the public and physicians is essential to reduce the number of perforations.

Adolescent

Medical waste. The growing issues of management and disposal.

When addressing the impact of medical waste management and regulatory controls on the health care industry, it is important to remember that as long as modern medicine continues to maintain and sustain its current quality of life and wellness standards, industry will continue to generate various byproducts that have adverse effects on both people and the environment. It is important, therefore, to carefully evaluate the impact of societal demands. Unless government, industry, environmental groups, and health care providers abandon their current adversarial relationships and work together to solve shared problems, there will be no improvement in the growing problem of medical waste. The long-term solutions to today's growing waste problems depend to a great extent on human factors and the willingness of industry, medical community, and governmental bodies to cooperate with each other, recognizing the cause-effect relationship of a continued demand for disposable products. There are many pieces to the waste management puzzle. Obviously, surgeons cannot perform surgery without exposure to blood, tissue or body fluids, and nurses cannot maintain asepsis without sterile products. Because the health care team cannot totally eliminate the source of medical waste, they must learn to more effectively manage and control it. Health care professionals must encourage industry and government to work together to develop standards for products and materials used as barriers and use more biodegradable materials. Health care facilities must learn to minimize the amount of medical waste designated as regulated or infectious. Segregating potentially infectious material from clean waste at the point of generation may reduce both volume and cost.

Humans

Regulations, standards, and guidelines.

Standards appearing in the Federal Register are law and are mandatory. Voluntary guidelines only constrain an institution if the guidelines are incorporated into the hospital's rules. Hospitals are required to have rules and regulations; however, they apply only to each individual hospital.

Hospital Administration

Appendicitis: the perforation rate when reviewed by decades in a general hospital.

Acute appendicitis at this medical center for 1984 was reviewed and compared with previous studies reporting 1944 and 1964. In 1984, the perforation rate was strikingly higher than the earlier years. It was zero in 1944, rose to 13.6 per cent in 1964, and to 31.4 per cent in 1984. One quarter of perforations in 1984 occurred during the first decade of life. In 1984, 14 per cent (10/70) of all patients with appendicitis were examined by a physician prior to eventual hospitalization; nine had perforated the appendix, representing 41 per cent of all perforations. Major factors responsible for the increase in perforations included (1) an increase in patients less than ten years old (a group at high risk for perforation), and (2) physician or patient delay in hospitalization. We suggest that physician and public education, which has proven effective in the past, should be reinstituted. Critical review of appendicitis should be carried out at individual institutions to identify, and thus, modify trends in this disease. Perforation increases morbidity and cost, yet is easily avoidable.

Adolescent