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Biomedical subjects

W C Butterfield

Publications and source records attributed to W C Butterfield.

At least 19 recordsLinked to original sources

Post-traumatic cysts of soft tissue.

Post-traumatic cysts of soft tissue, formed by crushing and shearing strains, usually occur at the junction of the subcutaneous fat and deep fascia. They become filled with serosanguinous fluid and lined with fibrous tissue. Chronic cysts may either remain stable or occasionally expand, much like a subdural hematoma.

Adipose Tissue

Abdominal exploration as a diagnostic procedure.

Diagnostic laparotomies performed during a five and a half year period in a 400-bed hospital were reviewed. Positive findings on physical examination, laboratory results, or x-ray findings were given one point each, making possible a range of points extending from zero to three for each patient. The number of positive laparotomies (those truly diagnostic) increased in a "linear" fashion with the point rating of each patient. No patients with a zero score had a laparotomy that was diagnostic, whereas 97 per cent of those with a score of three had positive laparotomy.

Abdomen

Experimental stress ulcers: a review.

The restraint model and other models for the production of experimental stress ulcers have been reviewed. The mechanism of experimental stress ulcers appears to depend on an interaction between the presence of acid, changes in mucosal circulation, an increase in the excretion of glycoproteins in the mucus, and a decrease in mitotic activity of the mucosal lining of the stomach. Factors enhancing ulceration are cold, starvation, increased acidity, burns, reflux of bile, endotoxin, adrenalectomy, and hemorrhage. Factors inhibiting ulceration are vagotomy, anticholinergics, elemental diets, vitamin A, antacids, prevention of bile reflux, corticosteroids, epinephrine and norepinephrine, serotonin antagonists, and immediate replacement of blood loss with low molecular weight dextran. The role of sepsis is unclear and more work is needed in this area. Ulcers from intracranial injury are usually associated with the hypersecretion of gastric acid. Stimulation of the hypothalamus, directly or indirectly, with resultant vagal stimulation is thought to be the responsible mechanism for the increase in acid.

Animals