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Biomedical subjects

W C Feng

Publications and source records attributed to W C Feng.

29 records · Page 2Linked to original sources

Aortic valve replacement (AVR): influence of age on operative morbidity and mortality.

Retrospective analysis of 306 patients following aortic valve replacement (AVR) was carried out between 1985-89. Patients were divided into two groups: group 1 patients were less than 70 years of age and group 2 were greater than 70 years of age. The multivariant analysis of risk factors showed the only increased risk for surgery was the NYHA class IV in either group. There was no overall difference in morbidity and mortality. The actuarial survival rate for group 2 patients was 95% at 1 year and 75% at 5 years. This was not different when compared for death in age- and sex-matched controls from the general population. AVR in the elderly is safe, the long-term result is good and it remains the treatment of choice unless there is an absolute contraindication.

Age Factors↗

Swan-Ganz catheter-induced massive hemoptysis and pulmonary artery false aneurysm.

Swan-Ganz catheter-induced massive hemoptysis and later pulmonary artery false aneurysm occurred in a patient with prosthetic mitral regurgitation. This patient was successfully managed by double-lumen endotracheal intubation, control of pulmonary hypertension, reversal of anticoagulation, mitral valve re-replacement, and transcatheter embolization. The pertinent literature is reviewed.

Aged↗

Spotted fever group rickettsiae in Dermacentor variabilis from Cape Cod, Massachusetts.

Spotted fever group (SFG) rickettsiae were identified by indirect immunofluorescent antibody tests in 1.1% of 6,956 specimens of Dermacentor variabilis collected on Cape Cod, Massachusetts. Forty-one of 45 rickettsial isolates were serotyped as Rickettsia montana, one as Rickettsia rickettsii, and three were unidentified. Studies of canines and humans with clinical evidence of spotted fever, and of healthy dogs with antibody to SFG rickettsiae, indicated that exposure of the canine population to R. montana was common but that R. montana was not involved in the etiology of spotted fever.

Animals↗

Natural infection of dogs on Cape Cod with Rickettsia rickettsii.

Four isolates of rickettsiae from sick dogs on Cape Cod, Mass., were serologically identical to isolates of Rickettsia rickettsii from human patients with Rocky Mountain spotted fever. The antigenic analysis used the indirect fluorescent-antibody test and antisera prepared in mice to each of the isolates and to reference strains of R. rickettsii and Rickettsia montana. Serological responses of infected dogs were specific for R. rickettsii, although antibodies to R. montana were also detected in the sera of most of the canines.

Animals↗

Knowledge-based segmentation of pediatric kidneys in CT for measurement of parenchymal volume.

PURPOSE: The purpose of this work was to develop an automated method for segmenting pediatric kidneys in helical CT images and measuring their volume. METHOD: An automated system was developed to segment the kidneys. Parametric features of anatomic structures were used to guide segmentation and labeling of image regions. Kidney volumes were calculated by summing included voxels. For validation, the kidney volumes of four swine were calculated using our approach and compared with the "true" volumes measured after harvesting the kidneys. Automated volume calculations were also performed in a cohort of nine children. RESULTS: The mean difference between the calculated and measured values in the swine kidneys was 1.38 ml. For the pediatric cases, calculated volumes ranged from 41.7 to 252.1 ml/kidney, and the mean ratio of right to left kidney volume was 0.96. CONCLUSION: These results demonstrate the accuracy of a volumetric technique that may in the future provide an objective assessment of renal damage.

Artificial Intelligence↗

Sternal wound infection after myocardial revascularization with internal mammary artery.

The use of the bilateral mammary artery in myocardial revascularisation in diabetic patients has been thought to increase the risk of sternal wound infection. We studied unilateral IMA grafting retrospectively in 701 consecutive patients to determine the incidence of sternal wound infection. One hundred and six patients were diabetic; 595 were non-diabetic. Both groups of patients were comparable for age, number of bypasses, and cardiopulmonary bypass time. No patient in the diabetic group developed mediastinitis; two patients of 595 in the non-diabetic group (0.3%) developed mediastinitis. Incidence of subcutaneous wound infection was slightly higher in the diabetic group than in the non-diabetic group (2% vs 0.3%) but was not statistically significant. We conclude that unilateral internal mammary artery grafting in diabetics is not associated with increased risk of sternal wound infection and should remain the conduit of choice for myocardial revascularization.

Adult↗