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Biomedical subjects

W C Haynes

Publications and source records attributed to W C Haynes.

12 recordsLinked to original sources

Esophageal strictures following endoscopic variceal sclerotherapy: clinical course and response to dilation therapy.

The authors evaluated the clinical course and management of 10 sclerotherapy patients with obliterated varices and symptomatic esophageal strictures. Strictures developed after 29 injections of 51 ml of sodium tetradecyl sulfate on an average of three sessions. Although the severity of dysphagia was variable, all patients were successfully managed with bougienage. To evaluate risk factors related to stricture formation a comparison was made with 14 nonstricture patients with obliterated varices. Multiple parameters of sclerotherapy were evaluated including total volume of sclerosant, number of injections, number of EVS sessions, volume of sclerosant, number of injections per session, number of esophageal ulcerations, and frequency of EVS treatments. No aspects of therapy clearly predicted the development of esophageal stricture.

Adult↗

A prospective comparison of anoscopy and fiberendoscopy in detecting anal lesions.

With the increase in rectal and perianal disease, thorough examination of this area is necessary in every patient with colorectal complaints. We compared the current fibersigmoidoscope and colonoscope with routine anoscopy in the detection rate of perianal pathology in 115 consecutive patients. Straight withdrawal and retroflexion in the rectum of the fiberoptic instruments led to lesion detection rates of 78% and 54%, respectively. The anoscope showed 99% of lesions. Anoscopy was easily learned and required less than a minute to perform. We conclude that anoscopy should be performed in every patient undergoing fibersigmoidoscopy or colonoscopy. Instructions in this procedure should be provided in all training programs.

Adult↗

Percutaneous endoscopic gastrostomy (PEG). A new procedure comes of age.

Our cumulative literature review suggests PEG is a simple, relatively safe, and cost-effective means of establishing enteral access for patients who qualify for long-term nutritional support. Tube placement can be achieved in 98% of patients, usually within 15 to 30 minutes without general anesthesia. The gastrostomy catheter can be easily removed when treatment is ended and conveniently replaced if accidentally dislodged. Complications occur in approximately 17% of patients, but only 3.0% are regarded as serious. No procedure-related deaths have been reported. PEG as the initial choice for feeding tube placement followed by surgical gastrostomy in patients in whom PEG is unsuccessful is a reasonable approach to nutritional management in appropriate patients. PEG for purposes of chronic gastrointestinal decompression and internalization of biliary drainage holds promise but requires further evaluation.

Gastroscopy↗

The long and short of flexible sigmoidoscopy: does it matter?

Physicians performing fiberoptic sigmoidoscopy may choose between a 35 and 60 cm instrument. Confusion and dispute exist concerning the advantages of one over the other. In an effort to resolve this question, 100 consecutive symptomatic patients were examined in an outpatient sigmoidoscopy clinic. Both the Olympus OSF-30 and Olympus OSF-60 flexible sigmoidoscopes were used on each patient alternately. Mean examination time, patient tolerance, diagnostic findings, instrument cost, physician training time, and insertion length were recorded and compared. The longer scope detected five more polyps and 25 additional cases of diverticulosis which were located beyond the reach of the shorter scope. The increased number of findings with the longer scope was expected; however, the increased number of polyps was not statistically significant. The additional number of findings with the longer scope was expected and with increased number of examinations the increased number of polyps may prove to be statistically significant. Neither instrument can substitute for colonoscopy in the overall management of colorectal neoplasms. We conclude that with adequate training and cost control, either instrument can be used for screening proctosigmoidoscopy; but the trend suggests a greater number of polyps are detected with the longer instrument.

Clinical Competence↗

Percutaneous endoscopic gastrostomy: new management of a difficult problem.

Under appropriate conditions, enteral feeding is the preferred method of nutritional management. Nasoenteric tube feeding may be adequate for short-term use but a more permanent indwelling gastrostomy tube is favored when long-term nutritional support is planned. PEG has several advantages over the surgical approach and should be considered the procedure of choice.

Contraindications↗

Spore formation by Bacillus popilliae in liquid medium containing activated carbon.

Haynes, W. C. (Northern Regional Research Laboratory, Peoria, Ill.), and Lenora J. Rhodes. Spore formation by Bacillus popilliae in liquid medium containing activated carbon. J. Bacteriol. 91:2270-2274. 1966.-Heretofore, it has not been found possible to evoke sporulation of Bacillus popilliae in liquid culture. We have discovered that sporulation will occur in tryptone-glucose-yeast extract broth shaken cultures if activated carbon (charcoal) is present during growth. The spores so engendered have survived drying in air and subsequent storage for several months as dry films and also in dry soil, sand, and a mixture of powdered calcium carbonate and talc. Furthermore, the longevity of cultures, even when spores are absent, is extended, in cultures containing activated carbon, to several weeks at a population of millions of cells per milliliter. This extension of life is the result of a marked change from rapid decline in numbers to an almost stationary population.

Bacillus↗