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Biomedical subjects

W C Peacock

Publications and source records attributed to W C Peacock.

14 recordsLinked to original sources

Computer-based animal record system in a nonhuman primate colony.

A relatively inexpensive microcomputer system was developed to store and manipulate clinical and pathologic data from a large colony of nonhuman primates. The programming for the system was designed so that the computer instructs users, who may have no knowledge of programming, how to enter data of all kinds and how to to command it to answer any ad hoc queries about the data. Minimum input from a professional programmer is required. As many as 4 investigators may use the system simultaneously by means of satellite terminals located in several areas throughout the facility. Most alphabetic data are coded, using 2- or 3-digit codes. More complex diagnostic data are coded, using the numeric codes of the Systematized Nomenclature of Medicine. presently, 17 record types encompasses all data entered into the computer. The system is functionally designed and about 50% operational at this time. This is the first description of an animal medical data system designed to exploit the lower costs and increased power of commercially available microcomputer packages.

Animals↗

Baseline blood chemistry determinations in the squirrel monkey (SAimiri sciureus).

Sera from 129 squirrel monkeys, Saimiri sciureus, were analyzed for 15 chemical constituents. The values obtained were then analyzed for statistical significance causing the following sets of variables: (1) colony-bred versus noncolony-bred, (2) karyotype (3) vendor, (4) sex and (5) dietary iodine supplementation versus nonsupplementation. Calcium, inorganic phosphorous, albumin, uric acid, blood urea nitrogen, glucose, alkaline phosphatase and potassium were high in colony-bred animals. Cholesterol, total protein and chloride were lower in colony-bred animals than in noncolony-bred animals. No differences were seen in total bilirubin, lactic dehydrogenase, serum glutamic oxaloacetic transaminase and sodium. When the noncolony-bred animals were separated by karyotype, total protein was higher and chloride was lower between animals from Peru versus from Guyana. Colombian animals had total protein values lower than Peruvian and lactic dehydrogenase values higher than Peruvian. Colony-bred Peruvian monkeys had serum glutamic oxaloacetic transaminase values higher than colony-bred Colombian monkeys. No differences were observed between monkeys from different vendors. Chemical constituents higher between noncolony-bred males and females were calcium and alkaline phosphatase. There were no differences observed for colony-bred males and females. Dietary iodine supplementation appeared to increase both total bilirubin and calcium.

Age Factors↗