PubMed Health⌕ Search

Biomedical subjects

W Cole

Publications and source records attributed to W Cole.

33 records · Page 2Linked to original sources
PubMed1986

The use of tryptophan in normal-weight bulimia.

Animal studies have implicated serotonin in the regulation of eating behavior. Hypothalamic serotonin receptor sites have been postulated to explain the inhibitory effect of serotonin on feeding behavior. This case study reports on the successful diminution of bingeing behavior in a normal weight bulimic female who was administered oral tryptophan, a serotonin precursor. The patient received a six week trial of tryptophan at a daily dosage of 20 mg/kg. A cessation of both the urge to binge and the behavior itself was noted. These preliminary findings are consistent with animal models suggesting the regulation of satiety is dependent on the inhibitory action of serotonin. Implications for the treatment of bulimic individuals are discussed.

Adult↗
PubMed1979

The relationship of health beliefs and a postcard reminder to influenza vaccination.

The relationship of certain health beliefs to influenza vaccination and the effect of a postcard reminder on vaccination rates was studied among 232 high-risk patients. In agreement with the Health Belief Model tested, the patients vaccinated believed influenza to be more serious, believed they were more susceptible to influenza, and believed the vaccine to be more efficacious than did patients not vaccinated. Those not vaccinated were less satisfied with their medical care and felt the vaccine was more expensive than those vaccinated. A postcard reminding patients of influenza vaccination was an effective way to increase the vaccination rate. Patients receiving the card had a 59.7 percent vaccination rate compared to a 30.0 percent rate among those not receiving the postcard. This study suggests that a reminder postcard is an effective means to promote influenza vaccination and that these beliefs are important determinants of vaccination behavior.

Attitude to Health↗
PubMedDate not supplied

Recent trends in morbidity and mortality rates for abdominal aortic aneurysms.

OBJECTIVES: To examine recent trends in mortality and morbidity rates from aortic aneurysms among Canadian seniors. DESIGN: Retrospective study. PARTICIPANTS: Men and women age 65 years or older who were hospitalized in Canada with a primary diagnosis of aortic aneurysm or whose underlying cause of death was aortic aneurysm. MAIN RESULTS: Unlike other circulatory diseases which have shown marked declines, mortality and morbidity rates from aortic aneurysms have remained constant over the last 10 years. Risks for male seniors are 4-5 times greater than for females. CONCLUSIONS: Since mortality and morbidity from aortic aneurysms have not decreased and screening offers potential benefits, costs and benefits of screening need to be quantified.

Aged↗