PubMed Health⌕ Search

Biomedical subjects

W D Shelp

Publications and source records attributed to W D Shelp.

At least 19 recordsLinked to original sources
PubMed1982

Amoxapine-associated rhabdomyolysis and acute renal failure: case report.

Amoxapine, a new tricyclic antidepressant, has been recently released in the United States and Europe. There has been limited experience with amoxapine overdose, and no serious reactions or sequelae were observed in the reported cases. A case of amoxapine overdose associated with rhabdomyolysis and acute renal failure is reported. Amoxapine overdose could cause convulsions or prolonged coma leading to atraumatic rhabdomyolysis and myoglobinuric renal failure. Direct muscle or renal toxicity from this drug and its metabolites should not be excluded until evidence to the contrary is available. Acute renal failure should be looked for in cases of amoxapine overdose.

Acute Kidney Injury↗
PubMed1980

Vasculitis in Goodpasture's syndrome.

Because of differing diagnostic criteria, a controversy exists as to whether vasculitis may occur in patients with Goodpasture's syndrome. Using strict criteria (pulmonary hemorrhage, glomerulonephritis, and antiglomerular basement membrane antibody), we found histological evidence of vasculitis in two of 18 patients with Goodpasture's syndrome. The vasculitis was found in kidney biopsy specimens. Clinically, these two patients did not differ from other patients who have Goodpasture's syndrome without vasculitis. The presence of vasculitis should not exclude the diagnosis of Goodpasture's syndrome.

Adolescent↗
PubMed1978

A model for planning health care in patients with end-stage renal disease.

Treatment modalities of end-stage renal disease (ESRD) patients include in-center dialysis, home dialysis, and kidney transplant. We present a model to account for all aspects of modality use to aid in planning regional facilities. Five years of data for 979 patients on dialysis in Wisconsin between 1970 and 1975 are used. The model shows movement (transit probabilities) from one modality to another, eg, transition from in-center dialysis to transplantation, and data were used to derive all transitional probabilities characterizing patient movement from one modality to another. Model and probabilities were used to predict number of patients in each modality in 1976, and the model was used to predict number of patients in each treatment modality through 1990. These figures may be used for planning regional facilities. Extrapolation of this model and derived probabilities for nationwide projections may be possible.

Adolescent↗