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Biomedical subjects

W D Wilcox

Publications and source records attributed to W D Wilcox.

29 records · Page 2Linked to original sources
PubMed1986

Systemic Hemophilus influenzae disease in children. A 10-year retrospective study of an urban hospital population.

A 10-year retrospective study of age-frequency, sites of infection, and pre-existing conditions in 297 children with Hemophilus influenzae (HI) disease seen at Grady Memorial Hospital from 1974 through 1984 is described. The majority of the patients were black (73%) and of lower socioeconomic status and were less than 2 years of age. Manifestations of HI disease were similar to those described in reports from other centers, with meningitis being the most common (56.7%). Epiglottitis was much less common in the present study than is generally reported. The death rate of all patients was 1.8 percent. The results of this study indicate that HI disease continues to be a significant risk in children less than 2 years of age.

Age Factors↗
PubMed1985

Direct and indirect blood pressure during exercise.

In 27 subjects, we compared rest and exercise blood pressure (BP) measurements determined directly by catheterization of the radial artery with simultaneous values obtained indirectly by auscultation of the brachial artery. As work increased, the systolic BP increased, whereas the diastolic BP did not change. Considering all comparisons, direct BP was greater than indirect BP by a mean of 29.0 mm Hg for systolic BP and 12.3 mm Hg for diastolic BP. As exercise level increased, the difference between direct and indirect systolic BP decreased whereas the difference between direct and indirect diastolic BP did not change. Both methods have advantages for assessment of BP response to exercise: normality of BP response is best assessed by auscultation, whereas beat-by-beat trends in BP are more accurately defined by the direct method.

Adolescent↗
PubMed1984

M-mode echocardiographic abnormalities in Rocky Mountain spotted fever.

Rocky Mountain spotted fever is a serious acute systemic illness frequently complicated by cardiac involvement. To evaluate the spectrum of myocardial dysfunction, we obtained M-mode echocardiograms on nine consecutive patients with Rocky Mountain spotted fever within 72 hours of admission. Seven of the nine patients had echocardiographic evidence of impaired left ventricular function; two of the seven had no other evidence of cardiac involvement. The extent of impairment of left ventricular function reflected the clinical severity of the illness. Left ventricular myocardial dysfunction is a frequent complication of Rocky Mountain spotted fever. Echocardiography may provide the only clinical evidence of cardiac involvement in these patients.

Child↗
PubMed1983

Range-gated pulsed Doppler ultrasonographic evaluation of carotid arterial blood flow in small preterm infants with patent ductus arteriosus.

Range-gated pulsed Doppler (RGPD) ultrasonography was utilized to study the effect of a patent ductus arteriosus (PDA) on carotid arterial blood flow in small preterm infants. Carotid arterial flow velocity studies were performed on 23 preterm infants, sampling right and left carotid arteries. Studies on seven infants after PDA ligation and on seven who developed no evidence of PDA were used as controls. A strong relationship was demonstrated between diastolic reversal in the carotid arteries and PDA. The results of this study indicate that the RGPD flow velocity curve from the carotid artery is more sensitive than M-mode echocardiography or clinical examination in detecting PDA, and that PDA in small preterm infants is associated with a distinct abnormality in the carotid arterial flow pattern.

Blood Flow Velocity↗
PubMed1980

Discrete subaortic stenosis: two-dimensional echocardiographic features with angiographic and surgical correlation.

Clinical and M-mode echocardiographic features of discrete subaortic stenosis are indirect and nonspecific. Cardiac catheterization and angiography have invariably been necessary for substantiation of the diagnosis. Our experience with two-dimensional echocardiography in 10 patients with discrete subaortic stenosis indicates that this technique is more sensitive than angiography for the recognition and characterization of the obstruction. Although catheterization is superior in determining the severity of obstruction, two-dimensional echocardiography is at least as sensitivie in assessing ventricular hypertrophy and contractility and is a superior technique for appreciation of the morphologic spectrum of the lesion causing discrete subaortic stenosis.

Adolescent↗
PubMed1980

Postoperative false aneurysm of left ventricle and obstruction of left circumflex coronary artery complicating enlargement of restrictive ventricular septal defect in double-outlet right ventricle.

A case is reported of double-outlet right ventricle (DORV) with restrictive subaortic ventricular septal defect (VSD) in which enlargement of the defect at the time of surgical repair was associated with the late postoperative development of a false aneurysm of the left ventricle. The enlarging fale aneurysm caused extrinsic compression of the dominant left circumflex coronary artery, with subsequent ischemia and infarction of the posterolateral left ventricle. The anatomy and surgical implications of restrictive VSD are discussed.

Child, Preschool↗
PubMed1979

Anomalous origin of left coronary artery from pulmonary artery in association with intracardiac lesions. Report of two cases.

Two cases are presented to illustrate the diagnostic and therapeutic dilemma when an anomalous origin of the left coronary artery from the pulmonary artery occurs with a hemodynamically significant intracardiac lesion. Hemodynamic alterations resulting from the associated intracardiac lesion may obscure the clinical features of the coronary arterial abnormality, and the appearance of normal coronary arterial distribution with left ventricular or aortic root angiography may create a false impression of a normal origin of the coronary arterial supply. A high index of suspicion may be the only lead to the detection of an anomalous origin of the left coronary artery from the pulmonary artery in association with an intracardiac lesion. In addition to the intracardiac lesion known to be associated with coronary arterial abnormalities, the question of anomalous coronary supply should be raised by the finding of poor left ventricular function or mitral insufficiency after operation (unexplainable by other causes), by the development of poor myocardial function during cardiac catheterization or anesthesia, or by the significant enlargement of a coronary artery seen during left ventriculography or supravalvular aortography.

Aortography↗