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Biomedical subjects

W Dölle

Publications and source records attributed to W Dölle.

At least 73 records · Page 4Linked to original sources

[Treatment of acute viral hepatitis with laevulose infusions (author's transl)].

Until 1962 all patients with acute viral hepatitis admitted to the Medical University Clinic at Marburg were treated with laevulose infusions. This treatment was discontinued in 1963. Follow-up examination of 109 patients with acute hepatitis who had been given laevulose infusions and 91 who had not (both groups being similar as to age and sex and average severity of the disease) revealed that there was no significant difference between the two groups with regard to the fall in transaminase levels during the first seven weeks after the onset of jaundice. Serum-bilirubin concentration was also similar. On the other hand, the abrupt fall in serum-bilirubin concentration in the second to third week of illness, so typical of the spontaneous course, occurred a week later in those who had been given laevulose infusions. Duration of the disease until normalization of transaminase and serum-bilirubin concentration was not favourably influenced by laevulose infusions. It is concluded that such infusions do not have a favourable effect on the course of acute viral hepatitis.

Acute Disease↗

[Toxic megaileum. Relapse of ulcerative colitis in the ileum following colectomy].

A 19 year old male patient suffered from ulcerative colitis and was colectomized 5 1/2 years ago. He presented now with an acute illness, characterized by massive discharges from the ileostoma, fever, leucocytosis, meteroism, melaena and a tender abdomen. A severe ulcerative inflammation of the total ileum was found. A "toxic megaileum" developed. At an operation the ileum was opened and drained. The patient recoverd under treatment with prednisolone, salazosulfypyridine, parenteral nutrition and Vivasorb. It is suggested that in this case the severe ileitis was due to the same disease which led to the total colectomy 5 1/2 years ago: ulcerative colitis.

Acute Disease↗

[Malabsorption caused by HBsAg-positive panareteritis nodosa].

A 36 year old man with panarteriitis nodosa (PAN) presented over a certain period of time meinly with gastrointestinal symptoms. He was HBsAg positive and a "reactive" hepatitis with histologically demonstrated. Arterial microaneurysms and stenoses were detected by angiography in the liver, kidney and small intestine. These findings were confirmed by autopsy. Vascular occlusions had caused infarctions of the small intestine as well as necroses and ulcerations of the large bowel. Chronic ischemia is considered as cause of the patient's malabsorption-syndrome. It is suggested, that cachexia of PAN may be partly due to malabsorption.

Adult↗