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W E DEACON

Publications and source records attributed to W E DEACON.

At least 19 recordsLinked to original sources

NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION.

Kellogg, Douglas S., Jr. (Communicable Disease Center, Atlanta, Ga.), William L. Peacock, Jr., W. E. Deacon, L. Brown, and Carl I. Pirkle. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J. Bacteriol. 85:1274-1279. 1963.-One type, obtained from the purulent exudate of acute gonorrhea was maintained by 69 selective in vitro passages, at which point the organisms produced infections in human volunteers. A predominance of clonal types found in laboratory strains and a lack of ability to infect human volunteers resulted from 69 nonselective in vitro passages. Physiological and serological characteristics of the clonal types are compared. We are now in a position to study Neisseria gonorrhoeae organisms in their virulent form.

Exudates and Transudates↗

Fluorescent antibody methods for Neisseria gonorrhoea identification.

The application of fluorescent antibody procedures to the identification of Neisseria gonorrhoeae-described in this paper-promises to be of very considerable value in the epidemiology of gonorrhoea. Although there is much still to be finally determined, particularly in relation to the exact nature of the antigenic reaction involved in these procedures, it appears that anti-N. gonorrhoeae conjugates may now be prepared and used for the identification of N. gonorrhoeae in 16-20 hours, as opposed to as long as 10 days with conventional cultural techniques. The "delayed fluorescent antibody method" is of especial value for the detection of gonorrhoea in females.

Antibodies↗