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Biomedical subjects

W E Dunkelberg

Publications and source records attributed to W E Dunkelberg.

11 recordsLinked to original sources
PubMed1980

DF-2 septicemia after splenectomy: epidemiology and immunologic response.

A case of DF-2 infection in an adult with septicemia, renal failure, and diffuse purpuric lesions with clotting abnormalities is presented. The patient had had splenectomy four years before, and had recently sustained a dog bite, both characteristics of previously reported infections caused by this gram-negative organism. Examination of the patient's immunologic response by the indirect fluorescent antibody technic revealed no IgM response and a significant IgG response. We found a positive serum titer in the patient's wife, who had been bitten by the same dog in the past. The presence of serum antibody to this organism may not be protective against subsequent exposure.

Animals↗
PubMed1970

Method for isolation and identification of Corynebacterium vaginale (Haemophilus vaginalis).

A method for the clinical isolation and recognition of Corynebacterium vaginale (Haemophilus vaginalis) is presented. Wet mount and stained characteristics of genital tract discharges, cellular and colonial morphology of the bacilli, inhibition by H(2)O(2), lack of a catalase, and fermentation of particular carbohydrates are the determinant factors. The method enables differentiation of the species from unclassified diphtheroids common to the genitourinary tract.

Bacteriological Techniques↗
PubMed1969

Volatile and cellular fatty acids of Haemophilus vaginalis.

The major volatile acid produced by Haemophilus vaginalis was acetic acid. The absence of propionate, butyrate, and cellular branched-chain fatty acids indicates that H. vaginalis is not related to Propionibacterium or Butyribacterium.

Acetates↗
PubMedDate not supplied

Inhibition of Corynebacterium vaginale by metronidazole.

Metronidazole [1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole], previously thought to only inhibit obligately anaerobic bacteria, was found in vitro, to inhibit the growth of 15 facultatively anaerobic strains of Corynebacterium vaginale (Haemophilus vaginalis) using agar disk diffusion and broth dilution methods.

Corynebacterium↗
PubMedDate not supplied

Corynebacterium vaginale.

Corynebacterium vaginale is a sexually transmitted organism which was first recognized in 1953. It appears to utilize glycogen stored in vaginal epithelial cells, causing a malodorous vaginal discharge characterized by an abnormally high pH (5.0 to 5.5) and composed mainly of epithelial cells and hordes of bacilli. Infected men are asymptomatic, carry the organism for an unknown period of time, and transmit it through intercourse. The organism requires five B-vitamins, purines, pyrimidines, and a fermentable carbohydrate; neither factors X nor V are required. It is not a member of genus Haemophilus and is not likely to be a Corynebacterium. Appearing mainly Gram-negative, it has many characteristics of Gram-positive organisms including its pattern of sensitivity to antibiotics and the possession of certain enzyme systems. As the cause of bacterial vaginitis, C. vaginale may be the most prevalent sexually-transmitted organism.

Drug Resistance, Microbial↗