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Biomedical subjects

W E Gager

Publications and source records attributed to W E Gager.

At least 19 recordsLinked to original sources
PubMed1985

Corneal endothelial morphology after anterior chamber lens implantation.

The morphologic features of the corneal endothelium were investigated by means of regional wide-field specular microscopy and computer-assisted morphometry in 13 eyes of nine patients who had undergone intracapsular cataract extraction with anterior chamber lens implantation more than one year previously. The endothelial cells in these patients demonstrated a significant increase in cellular elongation and the coefficient of variation in mean cell area and a significant decrease in the percentage of hexagonal endothelial cells when compared with age-matched controls (ten eyes of ten patients). The clinical implications of these long-term morphologic changes are unknown, but the changes may be indicative of an unstable endothelium or may be an early sign of continuing cell loss.

Aged↗
PubMed1984

Magnetic resonance imaging of the optic nerves and chiasm.

Magnetic resonance imaging (MR) of the optic nerves and chiasm was compared with computed tomography (CT) in 4 healthy volunteers, 4 patients without orbital or chiasmal abnormalities, and 4 patients with tumor (anterior clinoid meningioma in 2, optic nerve glioma in 1, and optic nerve sheath meningioma in 1). MR was found to be effective in demonstrating the optic nerves and related structures, particularly the intracanalicular portion of the nerve which is difficult to see with CT. Best results were achieved with partial saturation recovery (SR) images; inversion recovery (IR) and spin echo (SE) techniques were less successful because of decreased spatial resolution (in the case of SE) as well as difficulty in seeing the anterior clinoid processes. As axial views cannot always distinguish the ethmoid sinus tissue from the optic nerve, it may be necessary to employ both axial and coronal images.

Adult↗
PubMed1982

Empty-sella syndrome. Occurrence in childhood.

Primary empty-sella syndrome has been rarely reported in childhood. Substantial visual disturbance was accompanied by minimal endocrine dysfunction in an 8-year-old girl whose only other complaint was headache. This syndrome in children is associated with more dramatic signs and symptoms than have been reported for adults and may be associated with progressive destruction of pituitary reserve.

Age Factors↗
PubMed1982

Ischemic optic neuropathy associated with Crohn's disease.

A 24-year-old man with Crohn's disease suffered bilateral ischemic optic neuropathy following the resolution of an episode of "uveitis." Additional findings of corneal infiltrates, vitritis, retinovascular sheathing, and arthritis suggest an inflammatory basis for his ischemic optic neuropathy. Vasculitis as an extraintestinal manifestation of inflammatory bowel disease is a possible etiology. To our knowledge, the association of ischemic optic neuropathy and inflammatory bowel disease has not been previously reported.

Adult↗
PubMed1980

Computed tomography of the optic chiasm.

Using a CT/T 8800 scanner, axial and coronal images of the optic chiasm were obtained in a cadaver, 41 normal individuals, and six patients with symptoms of chiasmal glioma. The size and shape of each chiasm were determined. The normal chiasm appeared to be U- or boomerang-shaped in axial sections, and U- or dumbell-shaped in coronal sections. The average normal chiasm diameters were 1.8 cm (transverse) by 0.8 cm (anteroposterior) by 0.4 cm (vertical). The chiasm was globular and larger than 0.6 cm (vertical dimension) in all cases of chiasmal glioma. The abnormal chiasm can be distinguished accurately from the normal chiasm by computed tomography.

Cranial Nerve Neoplasms↗
PubMed1979

Cat optic nerve imaging with metrizamide.

Metrizamide is a water-soluble, nonionic radiocontrast medium that penetrates better into narrow subarachnoid spaces than do oily contrast media or gas. We performed metrizamide optic nerve thecography on five cats with iatrogenic orbital lesions. Optic thecograms successfully demonstrated displacement of the optic nerve, obstruction of the optic nerve sheath subarachnoid space, and extravasation of the contrast medium from a punctured optic nerve sheath. Metrizamide-induced seizures could be prevented by intramuscular preadministration of diazepam.

Animals↗
PubMed1978

Optic neuritis complicating measles, mumps, and rubella vaccination.

A 6-year-old boy developed bilateral optic neuritis with decreasing visual acuity 18 days after administration of live attenuated trivalent measles, mumps, and rubella vaccine. The patient was treated with oral corticosteroids. The optic neuritis resolved within several weeks and normal vision returned. An afferent pupillary defect persistent in the more severely involved eye for 14 months following vaccination.

Adult↗
PubMedDate not supplied

Optic nerve sheath imaging with metrizamide.

A technique is described for opacifying the optic nerve sheaths with intrathecally injected metrizamide. The clinical and investigational applications are discussed.

Animals↗