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Biomedical subjects

W E Meier

Publications and source records attributed to W E Meier.

At least 19 recordsLinked to original sources
PubMed1980

[Long-term follow-up of patients asymptomatic and expanding abdominal aortic aneurysms (author's transl)].

In a retrospective study, 268 patients with all three types of abdominal aortic aneurysms (AAA) were analyzed. They had been seen at the Surgical Clinic A of the University Hospital in Zurich, Switzerland, from 1961 through 1977. The follow-up included 97% of the surgical and all nonsurgical cases. This report is based on the analysis of the 167 surgically and 16 nonsurgically treated patients with asymptomatic (I) or expanding (II) AAA. Of the 16 patients not operated on, 15 died after a mean time of 13 months after examination, 57% due to rupture and 29% because of coronary heart disease. In the operative group, the 30-day perioperative mortality was 7% for the asymptomatic AAA and 14% for the expanding. Late mortality reached 25% for type I and 37% for type II after a mean survival time of 50 months. Of all surgically treated patients, 58% could be examined 1-14 (mean 4) years after aneurysmectomy. The cumulative survival rate for the 5th year reached 73% in the surgical asymptomatic group and 48% in the expanding or 62% for both; the nonsurgical group had a survival rate of only 6%. The results of the long-term follow-up are described in detail as well as the various factors related to arteriosclerosis or to surgery with statistically significant influence on prognosis. Comparison of the late results of all three types of AAA and confrontation with the spontaneous course of the disease emphasize the importance of early indication for operation.

Aorta, Abdominal↗
PubMed1977

[Pre- and postoperative Doppler-ultrasound measurements in carotid artery surgery (carotid artery Doppler) (author's transl)].

The evaluation of carotid artery perfusion with Doppler-ultrasound is based on semiquantitative measurements of blood flow in the terminal branches of the ophthalmic arteries (supratrochlear and supraorbital artery) and the common carotid arteries. Diagnosis is performed with a set of 8 parameters and informs about obstructions in the carotid artery as well as the collateral circulation. The method was applied on 1500 patients of whom 340 underwent angiography and has proved to be about 90% reliable. Its value in carotid artery surgery was evaluated with 62 extracranial reconstructive operations on 55 patients and 35 iatrogene anastomoses between the temporal superficial and a branch of the middle cerebral artery on 35 patients.

Arterial Occlusive Diseases↗
PubMed1976

[Effect of coronary flow reduction on the coronary flow distribution, the myocardial metabolism and left ventricular hemodynamics].

Myocardial blood flow, left ventricular performance, regional myocardial metabolites (ATP, CrP, lactate) and a-v differences of oxygen, lactate and pyruvate were determined in 6 open chest dogs with cannulated left coronary artery. A mean flow reduction from 92 to 43 ml/min/100 g heart weight resulted in marked heart failure accompanied by extensive flow reduction to the endocard with nearly 10 fold increase of lactate and a decrease of CrP content to 50% of control. In contrast, flow and metabolic parameters of the epicardial part changed only slightly. Furthermore, the DPTI/SPTI-ratio showed a good correlation with the subendocardial CrP content (r = 0.93, p less than 0.01).

Adenosine Triphosphate↗
PubMed1976

[A different approach in the treatment of aneurysms of the ascending aorta (author's transl)].

A safe method in therapy of the ascending aortic aneurysm by partial resection and reconstruction combined with reinforcement by a nylon net is described. Seven patients were operated upon without hospital mortality. Early operation is recommended, when there is only slight aortic insufficiency. In such a situation it is possible to reinforce the ascending aorta without ECC, to stabilize the progress of widening the ascending aorta and the aortic root.

Adult↗
PubMed1976

[Animal experiments with a new intracardial pacemaker electrode].

In order to reduce the rate of dislocation of intracardiac pacemaker electrodes, a new electrode was developed. The tip of this new electrode is helical and can be fixed between the trabecles of the right ventricle by clockwise rotation. Since the tip of this new electrode has no sharp hooks the myocard cannot be damaged by fixation.

Animals↗