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W E WILSON

Publications and source records attributed to W E WILSON.

At least 19 recordsLinked to original sources
PubMed1964

POWASSAN VIRUS: SUMMER INFECTION CYCLE, 1964.

Between May 1, and September 15, 1964, neutralizing antibody to Powassan virus was detected in sera from 163 of 464 forest mammals captured in the Powassan-North Bay area of northern Ontario. These included 159 of 358 groundhogs and four of 43 red squirrels. Acquisition of antibody by juvenile groundhogs occurred principally during July and August. Powassan virus strains were isolated from tick pools containing two to 15 Ixodes cookei per pool which were removed from eight of 91 groundhogs in three townships during May, July and August. Virus was also recovered from blood of two groundhogs during May. Powassan virus was re-isolated from five of six tick pools and two blood clots by inoculation of swine kidney tissue cultures. These findings strongly suggest that during 1964 Powassan virus was maintained in nature by a cycle involving groundhogs and I. cookei ticks.

Animals↗
PubMed1964

IMMUNOLOGIC STUDIES IN HUMAN ORGAN TRANSPLANTATION. I. OBSERVATION AND CHARACTERIZATION OF SUPPRESSED CUTANEOUS REACTIVITY IN UREMIA.

Twenty-eight patients with chronic renal diseases and uremia were investigated with respect to their cutaneous responsiveness to a panel of antigens expected to elicit immediate and delayed hypersensitivity reactions. Compared to a control group, there was a marked decrease in the incidence of responses of both types. Eighteen patients received renal allografts from members of the control group and were available for restudy in the postoperative period prior to the institution of adrenal steroid therapy. Each recipient acquired delayed responsiveness with specificity identical with that of the kidney donor. The donor group was reactive to 49 antigens to which the recipients were non-reactive preoperatively. Postoperatively, 40 of these reactivities were observed in the recipients. This successful demonstration of the transfer of immunologically competent tissue in association with renal transplantation indicates that the cause of depressed cutaneous hypersensitivity in uremia is not an inability of the skin per se to react.

Adrenal Cortex Hormones↗
PubMed1960

Neil S. DUNGAY.

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