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Biomedical subjects

W E Waters

Publications and source records attributed to W E Waters.

At least 91 records · Page 5Linked to original sources
PubMed1971

Epidemiology of headache and migraine in women.

During a survey of a defined community, 2,933 women aged 20 to 64 years were asked standard questions about headaches. Overall, 78·7% had headaches during the year immediately preceding the survey and this proportion decreased significantly with age. Random samples of subgroups with unilateral headaches, headaches preceded by a warning, and headaches accompanied by nausea were examined clinically. From these clinical diagnoses the prevalence of women with migraine during the previous year was estimated as 19%. Nearly half of those diagnosed as having migraine had never consulted a doctor because of headaches. Women with migraine and non-migrainous headaches kept diaries of all headaches and data are presented for the time and day of onset, severity, duration and relation of menstruation for both types of headache.

Adult↗
PubMed1970

Clinical significance of dysuria in women.

During a community survey 22% of women were found to have had dysuria in the previous year and half had had dysuria at some time in their lives. Various measurements were made in a random sample of 282 of these women. The means and the variances of the systolic and diastolic blood pressures in women with a past history of dysuria tended to be higher than in women who gave no such history. There were no significant differences in the means of plasma urea, plasma creatinine, and renal concentrating power between women with and without a previous history of dysuria, but a significant impairment of renal concentrating power was found in an additional group of 30 women who dated the onset of their dysuria to childhood.These findings suggest that urinary tract infection in adult women does not usually lead to progressive impairment of kidney function, whereas infection in childhood is more often associated with kidney damage.

Adult↗
PubMed1970

Controlled clinical trial of ergotamine tartrate.

A double-blind controlled clinical trial of cross-over design for the treatment of headache was conducted in 88 women identified during a community survey as having headaches with the features of migraine. Of 79 subjects who completed the trial, 40 benefited from oral ergotamine tartrate and 46 benefited from the placebo. There was no evidence that ergotamine in doses of 2 or 3 mg. was more effective than the placebo. Ergotamine aggravated the attack significantly more often than the placebo. Neither the colour of the tablets nor the order of therapy significantly affected the results of the treatment.

Adult↗
PubMed1969

Ten-year haematological follow-up: mortality and haematological changes.

In a 10-year follow-up study of 543 men and 180 women seen in a community survey in 1958 mortality was examined in relation to the 1958 haematological data, and 91% of the survivors were re-examined. Analyses based on the 1958 haemoglobin and packed cell volume estimations suggested that those with values near the mean may subsequently have lower death rates. Higher death rates occurred in those having low serum iron levels. Comparisons of haemoglobin concentrations and of packed cell volumes in 1958 and 1968 show correlation coefficients (r) between 0.30 and 0.60 in various subgroups.

Adult↗
PubMed1969

Asymptomatic significant bacteriuria in the non-pregnant woman. I. Description of a population.

The clinical, laboratory, and radiological findings in a group of 107 non-pregnant bacteriuric women and 88 controls have been compared. A previous history of urinary tract infection was more commonly obtained from the bacteriuric women. The means of the diastolic blood pressures, serum ureas, and erythrocyte sedimentation rates were significantly higher in the bacteriuric group, and acquired renal abnormalities were demonstrated in 18% of the bacteriuric women as compared with 4% of the controls. It is concluded that screening for asymptomatic bacteriuria in the adult non-pregnant female population in many instances fails to detect urinary tract infection at an early and reversible stage.

Adult↗
PubMed1969

Asymptomatic significant bacteriuria in the non-pregnant woman. II. Response to treatment and follow-up.

Short courses of nitrofurantoin and ampicillin produced an immediate cure in 80% of adult non-pregnant bacteriuric women. Of the subjects so treated, 55% remained cured at the end of one year. Over the same follow-up period 36% of untreated bacteriuric women developed a spontaneous remission of bacteriuria. Treatment failed to prevent the development of symptomatic infection, and the reinfections which followed successful treatment were more commonly associated with the development of symptoms than the persistent or relapsing infections in untreated or unsuccessfully treated subjects.It is concluded that a search for bacteriuria in non-pregnant women is unlikely to be of value as a preventive measure, since in many instances it fails to detect urinary tract infection at an early stage and since treatment by methods suitable for large-scale use is ineffective.

Adult↗