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W Esser

Publications and source records attributed to W Esser.

13 recordsLinked to original sources

QAlign: quality-based multiple alignments with dynamic phylogenetic analysis.

Integrating different alignment strategies, a layout editor and tools deriving phylogenetic trees in a 'multiple alignment environment' helps to investigate and enhance results of multiple sequence alignment by hand. QAlign combines algorithms for fast progressive and accurate simultaneous multiple alignment with a versatile editor and a dynamic phylogenetic analysis in a convenient graphical user interface.

Algorithms↗

[Grand mal series after Ecstasy abuse].

The consumption of the jet set drug Ecstasy (3,4-methylenedioxymetamphetamine, abbreviated to MDMA) by young people is increasing markedly. Parallel to this development, there is a large number of reports on severe neurological, psychiatric and medical complications following the use of Ecstasy. Seizures are among the most common clinical complications of the CNS following the ingestion of Ecstasy. Our report presents the case of a 21-year-old patient, who had a series of grand mal seizures after taking 12 tablets of Ecstasy. 36 hours after ingestion the substance MDMA was demonstrated at a level of 300 ng/ml in the serum and CSF. Following treatment with Clonazepam and under an adequate level of carbamazepine, no further seizures occurred. The diagnosis was difficult because the patient initially denied the consumption of drugs and the routine toxicological screening does not contain the substance MDMA.

Adult↗

[Sonographic visualization of the pancreatic duct before and after secretin stimulation: an aid in the diagnosis of chronic pancreatitis].

In 34 patients the diameter of Wirsung's duct was measured by real-time sonography before and after intravenous application of secretin. 25 of these patients, meeting special criteria, were chosen as normal controls; 9 patients had chronic pancreatitis. Normal subjects with an average duct diameter of 1.8 mm showed an average dilatation by about 89% to a mean value of 3.4 mm, mostly within five minutes. No dilatation was seen in patients with chronic pancreatitis (average duct diameter 2.9 mm), with the exception of one patient. The authors discuss the possibility of assessing pancreatic function and of detecting the presence of a rigid duct in a fibrotic pancreas by sonography. This confirms the usefulness of the sonographic secretin test as a reliable aid in the diagnosis of chronic pancreatitis.

Adult↗

[Icteric hepatitis in listeriosis?].

Icteric hepatitis was observed in a 21-year-old female patient. Titres of the agglutination reaction for listeria monocytogenes supported the likelihood of listeria infection. Further serological studies of potentially relevant viruses and bacteria remained negative.

Adult↗

[Ultrasonic tumor diagnosis of the stomach and intestines].

A cockade-like structure, consisting of an echo-free periphery and bright central echos, is often a typical sonographic sign of a gut-wall infiltration in the gastrointestinal tract. On principle, no distinction based on contour or structure can be made sonographically between neoplastic and inflammatory tissue. The recognition of such a cockade-like structure is of importance in patients, in whom no gut-wall infiltration is suspected. Within a period of 12 months cockade-like structures have been detected in the gastrointestinal tract of 20 patients. By extensive diagnostic methods (X-ray examination, endoscopy, laparotomy) a colon carcinoma could be detected in seven, a gastric carcinoma in seven, a pancreatic carcinoma, encroaching circularly upon the duodenum, in one, and a small intestine metastasis of an ovarian carcinoma in one instances. Three typical cockade-like structures in different parts of the intestinal tract are illustrated.

Adenocarcinoma↗

[The significance of dietary fat and fiber for the aetiology of colon cancer (author's transl)].

Dietary habits of 49 patients with colorectal carcinoma or precancerous adematous polyps were investigated and compared with age- and sex matched, healthy controls. The dietary fiber intake of the tumor group was not significantly lower than control. Tumour patients were found to eat more animal fat than controls, the difference not reaching statistical significance. By contrast, we found a highly significant difference in the ratio of daily dietary fat/fiber intake (p less than 0.001). The ratio was 19.1 +/- 1.1 in tumour patients and 14.5 +/- 0.6 in controls. It is concluded that in the genesis of colorectal carcinoma, the relation of dietary fat to fiber might be more important than the intake of these two dietary constituents in absolute terms.

Cellulose↗

[Death in inverted head position].

A 56 year old man was found suspended in a sack in a head down position. Circumstances and autopsy findings are discussed. The leading pathophysiological mechanisms causing death are thought to be asphyxia due to compression of the chest and insufficient blood supply to the heart due to the head down position. The pathophysiological dysregulation of circulation in a head down position is discussed.

Accidents, Home↗