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Biomedical subjects

W F Bergfeld

Publications and source records attributed to W F Bergfeld.

At least 91 records · Page 5Linked to original sources
PubMed1991

Fibrous papule of the nose with granular cells: two cases.

Two cases of fibrous papule of the nose (FPN) with granular cell features are presented and discussed. Both lesions have classic architectural features of FPN; however, the main stromal cells show large cytoplasmic granules of the type seen in granular cells. We are uncertain of the significance of these findings. Our hypotheses include a perifollicular granular cell reaction and a granular degenerative change of local dermal dendrocytes.

Granular Cell Tumor↗
PubMed1991

The cosmetic ingredient review self-regulatory safety program.

The CIR's 13-year history of cosmetic-ingredient safety review appears to have successfully accomplished its goal of reviewing in a scientific manner the safety of cosmetic chemical ingredients. The method of prioritization has allowed for the identification of the most frequently used and the most biologically active chemicals. To date, 310 cosmetic ingredients have been reviewed, and 33 ingredients are under current review. Although CIR does not have a safety-evaluation report available for every cosmetic ingredient in use, it has proved that CIR is a system of documentation, review, and analysis that can be used to address any safety problem that may exist with any cosmetic ingredient.

Cosmetics↗
PubMed1990

Prevention of hair growth in myocutaneous flap reconstruction.

Myocutaneous flaps play a prominent role in the immediate reconstruction of surgical defects following ablative oncologic procedures in the head and neck. Transfer of hair-bearing skin into the reconstructed upper digestive tract can be a major disadvantage associated with the pectoralis major flap. De-epithelialization of skin to the dermal level, removing the majority of skin appendages, can convert a myocutaneous flap to a "myodermal" flap. Platysma myocutaneous and myodermal flaps were grafted into the oral cavity of 13 dogs. Gross and histologic evaluation confirmed decreased hair growth in the experimental myodermal flap. Wound complications and graft survival were similar for both techniques. Diminished hair growth further supports the utility of myodermal flaps in hairy male patients undergoing upper digestive tract reconstruction.

Animals↗
PubMed1990

Squamous cell carcinoma of the nail bed: a clinicopathological study of 12 cases.

Twelve cases were reviewed of squamous cell carcinoma of the nail bed, with emphasis on the aetiological role of human papillomavirus (HPV) infection and radiation damage. Using a hybridization technique, similar HPV genomes were detected in a uterine cervical neoplasia and a subungual squamous cell carcinoma in the same patient.

Adult↗
PubMed1990

Mosaic hair color changes in alopecia areata.

This paper documents the mosaic hair color changes in two patients with extensive alopecia areata. The authors suggest that these changes are the end result of localized immunologic reactions directed against the melanocyte, resulting in a cytotoxic effect on the melanocytes and altering the hair color. Visually, the change is identified as patchy lightening, occasional depigmentation, and whitening of existing scalp hair. These changes reflect increased activity and progression of alopecia areata.

Alopecia Areata↗
PubMed1990

Myelodysplastic syndrome and transient acantholytic dermatosis.

Focal acantholytic dyskeratosis consistent with the clinical and histological features of Darier's type of transient acantholytic dermatosis occurred in a man with myelodysplasia. Topical steroids and systemic antihistamines provided temporary and moderate relief from pruritus, but failed to control the dermatosis.

Acantholysis↗
PubMed1990

Reticulate pigmented anomaly of the flexures (Dowling-Degos disease): a case report associated with hidradenitis suppurativa and squamous cell carcinoma.

We report the first case of reticulate pigmented anomaly of the flexures (Dowling-Degos disease) associated with hidradenitis suppurativa. Our patient also showed a squamous cell carcinoma of the groin, which is a rare complication of hidradenitis suppurativa. The relationship between Dowling-Degos disease and hidradenitis is discussed and the literature on squamous cell carcinoma and hidradenitis suppurativa is reviewed.

Carcinoma, Squamous Cell↗
PubMed1989

Eosinophilic cellulitis and eosinophilic pustular folliculitis.

This report describes a patient with a drug reaction and histologic changes of both eosinophilic cellulitis and eosinophilic pustular folliculitis. We propose that some cases of eosinophilic pustular folliculitis, like eosinophilic cellulitis, may occur as a result of a hypersensitivity phenomenon.

Cellulitis↗
PubMed1989

Malignant angioendotheliomatosis: an angiotropic lymphoma.

Malignant angioendotheliomatosis is a rare, systemic, usually fatal disease characterized by massive proliferation of large, neoplastic, mononuclear cells within the lumen of small blood vessels. Recent studies suggested that the tumor cells are of lymphoid origin. We studied two cases of malignant angioendotheliomatosis by Southern blot hybridization analysis that showed rearrangements of the immunoglobulin heavy chain and kappa light chain (case 2), indicating the presence of a monoclonal B cell lymphoma. Our results provide further evidence that malignant angioendotheliomatosis is an angiotropic lymphoma.

Aged↗
PubMed1989

Wells' syndrome.

Explore the source record for details and available documents.

Cellulitis↗
PubMed1989

Bullous systemic lupus erythematosus.

Two patients with bullous systemic lupus erythematosus are reported. In one, the disease appears to have been caused by hydralazine. The cutaneous lesions of bullous SLE have not been previously reported in drug-induced lupus.

Adult↗