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Biomedical subjects

W F Bradley

Publications and source records attributed to W F Bradley.

8 recordsLinked to original sources

Pediatric otolaryngology: a psychosocial perspective.

Physical illness in children is affected by a variety of factors unique to pediatrics. They include a child's developmental level, family environment and the presence of premorbid behavior patterns. Therefore, pediatric care requires special considerations pertaining to the patient-physician relationship and the potential for psychosocial dysfunction. Three case reports are presented to illustrate these concerns in treating children within the specialty of otolaryngology. Prompt identification of these factors and effective intervention in cases of psychosocial disturbance are challenging facets of the practice of pediatric otolaryngology.

Adolescent↗

Life response to Crouzon's disease.

This paper describes the life responses of two adult patients with facial deformities associated with untreated Crouzon's disease. Each patient has normal intelligence, and each has two children and close family relatives who exhibit variable degrees of Crouzon's disease. The impact of untreated facial deformity is considered, and recommendations are made for psychosocial management of these patients and their families.

Adaptation, Psychological↗

Morphometry of the male feline pelvic urethra.

The pelvic urethra and bladder of the male cat were examined for comparison with those of the male dog which have been previously studied. Morphometric data were generated and analyzed statistically to provide an objective basis for comparing regions and species. Tissue quantities in the body of the bladder were significantly different from the vesical neck. The vesical neck of the cat was significantly different from the canine vesical neck. The smooth muscle sphincter in the cat was better developed than in the dog, and the cat had longitudinal smooth muscle arranged to actively open the sphincter. The feline urethra had relatively more elastic fibers and less stratum cavernosum than the canine urethra. Since canine and feline urethrae are structurally different, physiological interpretations based on one of the species should not be applied indiscriminantly to the other.

Animals↗

Morphometry of the female feline urethra.

Tissues composing the lower urinary tract of the female cat were discribed and analyzed morphometrically. Statistical comparisons were made with the female dog using previously obtained canine morphometric data. Despite a superficial similarity, the cat differs from the dog in having a significant component of longitudinally oriented urethral smooth muscle and appreciably less striated urethral sphincter. It is suggested that the cat requires an active mechanism for overcoming continence due to an inherently smaller urethral lumen, compared to the dog. The implication of our morphometric findings is that urethral mechanics are different for the female cat and dog.

Animals↗

A long-term clinical trial of prazosin.

The efficacy of prazosin given either alone or in combination with polythiazide was assessed in a study of 50 outpatients with essential hypertension. Among the 29 who completed 42 months of therapy, blood pressure fell significantly in 76%. Of the 21 who dropped out of the study after 1 to 41 1/2 months, 43% showed improvement, 38% showed no change, and 19% showed worsening of hypertension. The most common side effects were lack of energy and weakness. Diabetics and alcoholics tolerated prazosin well. Of the 50 patients who started treatment with prazosin alone, only 23 required addition of polythiazide.

Adult↗