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Biomedical subjects

W F Michael

Publications and source records attributed to W F Michael.

7 recordsLinked to original sources
PubMed1974

Spinal myoclonus.

A case of rhythmic myoclonus affecting only the lower part of the body is described. This occurred as an acute self-limiting illness. The changes in the cerebrospinal fluid (CSF) suggested a viral infection. Clinical and electrophysiological findings indicated that the involuntary movements were arising at spinal level and were independent of suprasegmental influences. There are few previously reported cases of spinal myoclonus, all different in various respects from the present one, which is reminiscent of the results of experimental inoculation of virus into feline spinal cord.

Action Potentials↗
PubMed1974

Posterior fossa aneurysms simulating tumours.

Seven cases of aneurysm of the vertebral and basilar arteries, in which the clinical features suggested a diagnosis of posterior fossa tumour, are presented. Their clinical manifestations and the difficulties of diagnosis are discussed. These lesions may mimic cerebellopontine angle tumours or brain-stem gliomas, or, less commonly, the picture is one of a compressive lesion at the foramen magnum. The need for vertebral angiography is emphasized. Exploratory surgery carries a high risk, and is to be avoided.

Adult↗
PubMed1970

Changes in pattern-evoked responses in man associated with the vertical and horizontal meridians of the visual field.

1. Averaged responses have been recorded from an array of ten scalp electrodes over the occipital cortex in man to the reversal of a black-and-white checkerboard pattern, presented in different octants of the visual field.2. In all subjects a prominent wave was seen, with a peak latency of about 100 msec, which showed consistent and systematic changes with variation in the position of the stimulus in the visual field.3. With stimulation of the octants next to the vertical meridian, this component was of large amplitude, while with stimulation of the octants next to the horizontal meridian, it was small and inconspicuous.4. With upper field octants, the peak at 100 msec was surface-negative, while with lower field octants it was reversed in polarity.5. The occipital response was largest 5 or 7.5 cm above the inion, and the amplitude recorded 3 cm lateral to the mid line was larger over the hemisphere contralateral to the half field being stimulated than ipsilaterally.6. These findings are discussed in relation to the underlying anatomy of the visual cortex, and it is concluded that these responses are likely to arise mainly from extra-striate areas.

Adult↗