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Biomedical subjects

W G Maxymiw

Publications and source records attributed to W G Maxymiw.

15 recordsLinked to original sources
PubMed1992

B-cell lymphoma presenting as a midfacial necrotizing lesion.

A case of midfacial necrotizing lesion (midline nonhealing granuloma) is reported. Paraffin- and frozen-section immunocytochemistry suggested a tumor of B-cell lineage and was confirmed by Southern blot analysis that disclosed an immunoglobulin heavy chain gene rearrangement with no evidence of T-cell receptor genetic aberration. The tumor was of B-cell lineage despite the tumor site and the angiocentric pattern, which are typically seen with peripheral T cell lymphoma with this presentation.

Aged↗
PubMed1991

Postradiation dental extractions without hyperbaric oxygen.

This study examined the incidence of osteoradionecrosis after tooth extraction with low-epinephrine or epinephrine-free, nonlidocaine local anesthetics and conservative surgical techniques. Estimates of the absorbed radiation dose on irradiated alveolar bone were made by reviewing radiotherapy records. This investigation included 72 patients ranging in age from 22 to 80 years (median 57.4 years). We removed 449 teeth. Analysis of radiotherapy check films revealed that only 196 teeth (44%) were included within the treatment volume. The median prescribed tumor dose was 50 Gy (range 25 to 84 Gy) in 20 fractions (range 10 to 37), with a median dose per fraction of 2.5 Gy (range 1.88 to 3.14 Gy). Follow-up time ranged from 68 days to 19.3 years (median 4.8 years). No instances of osteoradionecrosis occurred as a result of dental extraction with this conservative method.

Adult↗
PubMed1990

Ameloblastic carcinoma of the maxilla metastatic to the mandible. Case report.

A case of maxillary ameloblastic carcinoma metastatic to the mandible is presented. Of 33 cases of ameloblastic carcinoma reported in the English literature 10 have occurred in the maxilla. Of these, none produced mandibular metastases. The authors review the literature, describing clinical presentation, histological appearance, and treatment of this rare lesion.

Ameloblastoma↗
PubMed1989

The role of dentistry in patients undergoing bone marrow transplantation.

It is imperative that a comprehensive dental examination should be performed in all patients who are to undergo a bone marrow transplantation. Such assessments should be carried out prior to and after the transplantation procedure. This paper addresses the implications of marrow transplantation and the impact on dental treatment. The side-effects of transplantation chemotherapy, radiation treatment and graft versus host disease and their impact on the oral cavity are also discussed in this paper.

Bone Marrow Transplantation↗
PubMed1989

The immediate role of the dentist in the maxillectomy patient.

It is imperative that comprehensive planning takes place for the potential maxillectomy patient. Input from the dentist is required for all stages of the procedure, from initial consultation to placement of the final prosthesis. By utilizing an interim dental prosthesis (splint), the impact of tissue loss, wound fibrosis and neurological damage can be minimized. In this paper, the authors address the initial stage in the treatment sequence, the surgical splint.

Humans↗
PubMed1989

The role of dentistry in head and neck radiation therapy.

In the adult patient, oral complications of cancer radiotherapy stem from the deleterious effects of radiation on salivary glands, oral mucosa, mandibular musculature and alveolar bone. Clinical consequences of such treatment include xerostomia, rampant dental decay, mucositis, taste loss, osteoradionecrosis, infection, trismus, and nutritional stomatitis. These alterations to the normal state occur both during and after completion of head and neck radiation. Fig. 1 outlines the time frame involved in the development of each particular problem. In the past 20 years, many changes have occurred in the management of patients receiving radiation therapy. The traditional regimen of dental care in these patients was one of extracting all teeth encompassed by the radiation field. However, 15 years ago, this concept was questioned due to the incidence of post radiation caries (PRC) outside the zone of irradiation. The purpose of this paper is to review the major consequences of radiation treatment to the head and neck as well as outline the role of the dentist in the management of these patients.

Humans↗