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Biomedical subjects

W Güthoff

Publications and source records attributed to W Güthoff.

7 recordsLinked to original sources
PubMed2002

Amebic liver abscess--rare need for percutaneous treatment modalities.

BACKGROUND: Given the often unspecific symptoms of amebic liver abscess, an analysis was done to recognize the most common patterns of presentation. Since treatment recommendations are still inconsistent comparing conservative and interventional treatment modalities, we evaluated treatment modalities in our patients. METHODS: A retrospective case series of all patients with confirmed amebic liver abscess was conducted. Age, sex, country of origin or travel, symptoms, and physical and laboratory findings were recorded. Particular attention was given to the need for interventional measures. RESULTS: 62 patients were reviewed, and nearly all of them (95%) had a travel history. The most common findings were fever (97%), abdominal pain (95%), and hepatomegaly (79%). 11% still had no amebic antibodies on presentation but an increase in the follow-up examinations. In 5% needle aspiration was performed to allow differentiation between amebic and pyogenic etiology. Metronidazole alone quickly cleared symptoms in 92% of the patients. In 8% only, there was a therapeutic need for interventional procedures (3% already ruptured, 5% large abscess formation with the danger of rupture). CONCLUSIONS: In travelers with fever, abdominal pain, and hepatomegaly amebic liver abscess must be considered. Medical treatment with metronidazole is effective in more than 90%. Only in very few cases there is a need for invasive therapeutic modalities.

Abdominal Pain↗
PubMed1991

[Hepatitis B infections in families of carriers].

To examine the transmission of hepatitis B virus in families of carriers of hepatitis B surface antigen epidemiologic and serologic data were obtained on 209 household contacts of 106 carriers. 97 relatives (46.4%) showed signs of infection, 39 became chronic carriers too. Brothers and sisters are at the highest risk of infection within the families. Household contacts of chronic carriers should be considered a high-priority group to receive the hepatitis B vaccine.

Adult↗
PubMed1990

[Hygienic hospital arrangements for the care of patients with acute and chronic viral hepatitis B].

The authors suggest a procedure for the treatment of patients with acute or chronic HBV infection (virus of hepatitis B) which did not lead--according to a special investigation of the hygiene service--to nosocomial infection. The results apply, however, only to the specially infection-oriented area of medical clinics, not to others such as e.g. dialyzation centres. There, due to generally known special features of the working regime and basic disease, it did not prove possible to prevent in all patients infection with the hepatitis B virus.

Acute Disease↗
PubMed1990

[Halothane hepatitis in the differential diagnosis of postoperative jaundice].

Based on a case report the necessity of including halothane hepatitis in differential diagnosis of postoperative jaundice is described. Even in this case report, the diagnosis is a synopsis of the case history, clinical and biochemical findings and exclusion of other causes of disease. The detection of antibodies to halothane-altered hepatocyte components is at present only possible in a few special laboratories and does not succeed in all cases. Confirmation of the connection between halothane exposure and liver damage is of vital importance for the patient because a second exposure to halothane may result in fulminant hepatic failure. In choosing the appropriate anaesthetic method, other halothane anaesthesias carried out a short time ago should be considered.

Chemical and Drug Induced Liver Injury↗
PubMed1990

[Hospital hygiene measures in the care of cholera patients].

The hygienic precautions taken by a hospital are presented by the example of a cholera infected patient from Vietnam. Also in the future the import of single cholera cases will be inevitable as a consequence of the fast modern communication. But the hygienic standards valid for the GDR health service are well suited to prevent cholera from distribution.

Adult↗