Biomedical subjects

W Gast

Publications and source records attributed to W Gast.

39 records · Page 3Linked to original sources

PubMed1979

[The Sézary syndrome--an erythrodermic T-cell-lymphoma].

Report on a 75-year-old patient with Sézary syndrome which is characterized by the following leading symptoms: Erythrodermia, leukocytosis, circulating atypical lymphocytes with cerebriformous nuclei (Sézary cells) and swollen lymph nodes. Light microscopic and electron microscopic findings refer to a transitory situation of the Sézary cells from the reactive character to the (pre)neoplastic one. The disease is classified by T-(helper)cells as a low grade non-Hodgkin-lymphoma in parallel to mycosis fungoides and in general it finishes lethally after a course of 5 to 8 years. Apart from local steroid ointments and UV-irradiations the internal application of steroids, in the late stage if necessary in combination with cytostatics is recommended for therapy.

Aged↗

PubMed1979

[Trends in some treatment-criteria of patients of a dermatological children-ward (author's transl)].

In comparative studies on some treatment-criteria of patients of a dermatological children-ward between 1967, 1969, 1971, 1973, 1975 and 1977 we found a tendency to increased out-patient-treatment, a reduction in period of clinical sojourn and a significant increase in patients drug consumption. Most important reasons of this development are the following: Temporary decrease of birth rate in GDR; increased capacity of out-patient-treatment in the Leipzig-area; application of more effective drugs; improvements in management of clinical treatment. About 50% of treated in-patients are 0 to 3 years old. The great importance of a qualified dermatological treatment for success of clinical sojourn on a children-ward is underlined.

Adolescent↗

PubMedDate not supplied

[Phagocytic activity of granulocytes after UV-irradiation].

The effect of UV-irradiation on three functions of human isolated granulocytes (viability, phagocyte activity and capacity to reduce nitrotetrazolium blue) was investigated. The phagocytosis appeared to be the most sensitive function. The number of phagocytic cells was decreased under UV-doses as low as 0.63 kJ.m-2. Cell lethality was increased under UV-doses 4.32 kJ.m-2 and higher. The capacity to reduce nitrotetrazolium blue was uneffected even at the dose as high as 10.17 kJ.m-2.

Granulocytes↗