CBF evaluation before and after ketamine or brietal activation of the epileptic discharges.
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Biomedical subjects
Publications and source records attributed to W Graban.
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Aim of this study was to evaluate the significance of 99mTc-MIBI scintigraphy in detection of parathyroid adenomas in patients with primary and primary recurrent or persistent hyperparathyroidism after surgical treatment. The images of the neck and mediastinum were taken 20 minutes and 2 hours after i.v. injection of the radiopharmaceutic. Result of the scintigraphy was defined as positive when the initial high 99mTc-MIBI uptake persistent in the region of the neck or mediastinum. At this time the radioactivity from thyroid gland declined significantly. Parathyroid adenoma was confirmed by surgery in 10 out of 12 cases diagnosed by scintigraphy. Parathyroid imaging using 99mTc-MIBI is a promising procedure in the preoperative localisation of parathyroid adenomas in patient with hyperparathyroidism.
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The authors present one case of pheochromocytoma which was visualized during renal angioscintigraphy using 99mTc-Sn DTPA. An area of increased radioactivity above the left kidney suggested a well-vascularized mass supporting the clinical suspicion of a pheochromocytoma on the left, which was proved by abdominal angiography. During the operation the pheochromocytoma was removed.
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The significance of scintigraphic examination in four patients with hyperfunction of adrenal tissue after total adrenalectomy is described. The scintigraphic examination was done 7--8 days after the injection of 1 mCi of 131I-19-iodocholesterol using the Jumbo Thoshiba 202 scintillation camera and Informatek SIMIS 3 data processing system. Noticeable concentration of 131I-19-iodocholesterol occurred in all four patients of, in three cases in the region of the right adrenal gland and in one case in the region of the left one. Scintigraphic examination confirmed the clinical hypothesis that of cushing's syndrome recurred in these patients because of hyperfunctioning adrenal tissue left in the body after the operation. This diagnosis was given confirmed in two cases undergoing repeated operations. The scintigraphic examination allowed accurate localization of the adrenal tissue and facilitated finding it during the next operation. The authors believe that adrenal scintigraphy is at the present time one of the best methods of locating the hyperfunctioning adrenal tissue left in the body during total adrenalectomy.
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Described below is the radioisotope method of examining the patency of oviducts using a solution of 133Xe. Scintigraphic pictures of the uterine cavity and oviducts were obtained with a Jumbo Toshiba gamma-camera; they were subsequently analysed by an Informatek SIMIS-3 data processing system. A total of 30 women aged between 20 and 36 with primary or secondary infertility were examined. The patency of oviducts and the shape of the uterine cavity was assessed on the basis of: the overall picture of the activity of 133Xe in the uterine cavity and oviducts, the isocontours of the overall picture, curves of increasing and decreasing activity in the fallopian tubes, and the spatial picture of activity distribution in the uterus and fallopian tubes. The results of the examinations corresponded in all cases with the diagnosis made on the basis of hysterosalpingography. An advantage of the isotope method of examining the patency of fallopian tubes and the shape of the uterine cavity is the fact that it is an examination of a dynamic nature, completely safe for the patient and exposes the patients to a considerably lower dose of irradiation than during hysterosalpingography.
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