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Biomedical subjects

W H Clem

Publications and source records attributed to W H Clem.

9 recordsLinked to original sources

The use of radiographs in periapical surgery.

The purpose of this case report is to demonstrate the importance of radiographic examination before suturing in periapical surgery. Corrective surgery was performed to eliminate excess amalgam left in the periapical region 6 years before. The result was favorable and demonstrates the importance of radiographic examination before flap repositioning and suturing. A roentgenogram should always be made before suturing and dismissal to verify the removal of amalgam particles and to confirm that no alteration is needed.

Apicoectomy↗

An evaluation of etiologic factors in 382 patients treated in a postgraduate endodontic program.

A survey was completed to determine and to evaluate the reason for endodontic treatment performed by endodontic residents at the Baltimore College of Dental Surgery, University of Maryland at Baltimore. On the basis of patient data and the reasons for endodontic treatment, as stated by the treating residents, the results showed that necrotic pulp and irreversible pulpitis were the most frequent reasons for endodontic therapy. Other reasons for treatment included restorative considerations, retreatment, and trauma. The majority of cases involved posterior teeth, and the average age of patients was 40.0 years. The frequency by arch demonstrated approximately equal distribution between maxillary (54.8%) and mandibular (45.2%) teeth. A total of 224 (58.6%) of the 382 patients surveyed had preoperative pain.

Adolescent↗

Inhibitory effect of saliva on glutamic acid accumulation by Lactobacillus acidophilus and the role of the lactoperoxidase-thiocyanate system.

Clem, W. H. (University of Washington, Seattle), and S. J. Klebanoff. Inhibitory effect of saliva on glutamic acid accumulation by Lactobacillus acidophilus and the role of the lactoperoxidase-thiocyanate system. J. Bacteriol. 91:1848-1853. 1966.-Saliva contains an antimicrobial system which inhibits the growth of Lactobacillus acidophilus, as well as a number of other organisms, in complete growth medium. This antimicrobial system consists of the salivary peroxidase (lactoperoxidase) and thiocyanate ions, and requires the presence of H(2)O(2). Saliva inhibits the accumulation of glutamic acid and certain other amino acids by resting cells. This effect of saliva is decreased by dialysis, and thiocyanate ions restore the inhibitory effect of dialyzed saliva. The inhibitory effect of saliva is decreased by heat (100 C, 10 min), and lactoperoxidase restores the inhibitory effect of heated saliva. Thus, the inhibition of glutamic acid accumulation by saliva appears to be due in part to the lactoperoxidase-thiocyanate antimicrobial system. H(2)O(2) increases the inhibitory effect of both saliva and the lactoperoxidase-thiocyanate system on glutamic acid accumulation. The inhibition of glutamic acid accumulation is not preceded by a loss in microbial viability. The glutamic acid accumulated by L. acidophilus under the conditions employed remains largely (over 90%) as free glutamic acid. This suggests that saliva and the lactoperoxidase-thiocyanate-H(2)O(2) system inhibit the net transport of glutamic acid into the cell.

Carbon Isotopes↗