PubMed Health⌕ Search

Biomedical subjects

W H Radentz

Publications and source records attributed to W H Radentz.

16 recordsLinked to original sources

Fungal skin infections associated with animal contact.

Zoophilic dermatophytes are fungal organisms that primarily infect animals but occasionally infect humans. The most common of these are Microsporum canis and Trichophyton mentagrophytes. The clinical lesions of zoophilic fungal infections are more inflammatory than those caused by the typical anthropophilic fungi normally transmitted from person to person. To diagnose zoophilic fungal infections, a potassium hydroxide preparation of the skin scrapings may be examined microscopically or a culture may be obtained. Small lesions located anywhere except on the scalp may be treated with a topical antifungal agent. Oral griseofulvin is preferred for the treatment of scalp infections and extensive cutaneous infections.

Animals↗

Opportunistic fungal infections in immunocompromised hosts.

Fungal infections in immunocompromised hosts cause major morbidity and mortality. The Candida and Aspergillus species are the most common causes, but many rarer organisms, once considered "contaminants," are being reported. The number of patients who receive immunosuppressive agents for the treatment of malignancy or for organ transplantation is increasing as well as the potential for local or disseminated fungal infections. The diagnosis of these infections is often difficult and the existing methods for treatment are often ineffective. A high degree of suspicion to identify fungal infections and to prompt initiation of treatment must be maintained if the survival rate of these patients is expected to improve.

Amphotericin B↗

Phaeohyphomycotic cutaneous disease caused by Pleurophoma in a cardiac transplant patient.

A 56-y-old female cardiac transplant patient treated with cyclosporine and prednisone noted the onset of three nontender red nodules on the legs and arms after gardening. Biopsy of all lesions revealed inflammatory cells and hyphal elements in the dermis. The dematiaceous fungus cultured from biopsy tissue was a pycnidial-forming organism of the genus Pleurophoma. The lesions responded to the topical application of miconazole.

Female↗

The 'fixed' removable partial denture: report of case.

Careful monitoring of tissue that had been the site of three previous surgical procedures was necessary, but the patient needed a functional, esthetically acceptable prosthesis. The Andrews bridge was selected because it combines the stabilizing qualities of a fixed prosthesis with the accessibility to the tissues of a removable prosthesis. The recurring nature of the verrucous carcinoma along with extensive tissue loss were additional factors in selecting this appliance. The final results satisfied all the criteria. The patient has been seen at regular follow-up visits for 2 years since the last surgical procedure and there has been no clinical change in the previously involved tissue. The patient has tolerated the prosthesis well and is satisfied with her appearance.

Carcinoma, Papillary↗

A survey of factors possibly associated with cervical abrasion of tooth surfaces.

The study indicates that cervical abrasion is related in some way to a factor or factors associated with the initial stages of the tooth-brushing procedure. The evidence, furthermore, demonstrates that an excessive use of dentifrice habitually placed, undiluted, on the same area of the mouth, may produce the abrasion. In view of this evidence, it would seem prudent to advise patients to use decreased quantities of dentifrice and to initiate the brushing procedure on the occlusal surfaces of the teeth to effect a dilution of the dentrifrice. The same effect might be accomplished by alternating the initial placement of the brush between the quadrants to more evenly distribute the abrasive effect. The high percentage of these lesions found in this young age group demonstrates a higher prevalence of the lesion in a younger age group than was previously suspected. We can further conclude that cervical abrasion is related to age and gingival recession. Furthermore, the study indicates that patients who exhibit cervical abrasion have less plaque and the lower bleeding scores than those who do not.

Adolescent↗

Human lymphoproliferative reaction to food products. Possible role in periodontal inflammation.

Extracts of corn and some nuts were found to ubiquitously stimulate both adult and newborn cord blood lymphocytes to transform and produce a factor chemotactic for monocytes. This indicates that corn and nuts contain a mitogen and are potential stimulators of the cellular immune response. The exposure of lymphocytes to this mitogen in vivo might trigger a destructive inflammatory reaction in the surrounding tissues. These findings, therefore, suggest that foods such as corn and nuts may be responsible for some periodontal abscesses and may be contributing factors to the development of intrabony alveolar lesions and chronic periodontitis.

Cell Division↗